PDF(Pubmed)
Abstract：
Macular dystrophies (MDs) constitute a collection of hereditary retina disorders leading to notable visual impairment, primarily due to progressive macular atrophy. These conditions are distinguished by bilateral and relatively symmetrical abnormalities in the macula that significantly impair central visual function. Recent strides in fundus imaging, especially optical coherence tomography (OCT), have enhanced our comprehension and diagnostic capabilities for MD. OCT enables the identification of neurosensory retinal disorganization patterns and the extent of damage to retinal pigment epithelium (RPE) and photoreceptor cells in the dystrophies before visible macular pathology appears on fundus examinations. It not only helps us in diagnostic retinal and choroidal pathologies but also guides us in monitoring the progression of, staging of, and response to treatment. In this review, we summarize the key findings on OCT in some of the most common MD.
摘要：
黄斑营养不良（MD）构成了导致明显视力损害的遗传性视网膜疾病的集合，主要是由于进行性黄斑萎缩。这些情况的特征在于黄斑中的双侧和相对对称的异常，这些异常显着损害了中枢视觉功能。眼底成像的最新进展，尤其是光学相干断层扫描（OCT），增强了我们对MD的理解和诊断能力。OCT能够在眼底检查中出现可见的黄斑病变之前，识别神经感觉视网膜紊乱模式以及对营养不良中的视网膜色素上皮（RPE）和感光细胞的损伤程度。它不仅可以帮助我们诊断视网膜和脉络膜病变，还可以指导我们监测疾病的进展，分期，以及对治疗的反应。在这次审查中,我们总结了OCT在一些最常见MD中的关键发现。
