Abstract：
The study evaluated the effects of three different primary treatment protocols on maxillary growth in patients aged 5 years with complete unilateral cleft lip and palate (UCLP). The secondary objective was to assess the influence of initial cleft severity, family history of class III, and status of permanent lateral incisor on maxillary growth. In total, 54 patients with non-syndromic complete UCLP were included and grouped as follows: group An underwent lip adhesion, cheilorhinoplasty associated with tibial periosteal graft for hard palate repair, and finally veloplasty; group B underwent lip adhesion, then cheilorhinoplasty with intravelar veloplasty, and finally a hard-palate repair; group C underwent cheilorhinoplasty with intravelar veloplasty and then a hard-palate repair. Five-year maxillary growth was assessed on dental models, both clinically and digitally. No difference was found with GOSLON-Yardstick scoring. Five-year measurements showed that group C tended to have the best maxillary arch morphology (p = 0.012). Initial cleft severity did not impact maxillary growth, but status of permanent lateral incisor and family history of class III did (p = 0.019 and p = 0.004, respectively). In patients aged 5 years, the two-stage approach appeared to be the least detrimental to growth development. Predictive factors for growth retardation included the absence of lateral incisor and a family history of class III.
摘要：
该研究评估了三种不同的主要治疗方案对5岁完全单侧唇腭裂（UCLP）患者上颌骨生长的影响。次要目标是评估初始裂隙严重程度的影响，III类家族史,永久侧切牙对上颌生长的影响。总的来说,纳入54例非综合征性完全性UCLP患者，分组如下：A组进行了唇粘连，唇鼻成形术与胫骨骨膜移植相关，用于硬腭修复，最后进行瓣膜成形术；B组进行唇粘连，然后是唇鼻成形术和腔内静脉成形术,最后进行硬腭修复；C组接受唇鼻成形术和腔内静脉成形术，然后进行硬腭修复。在牙科模型上评估了五年的上颌骨生长，临床和数字。GOSLON-Yardstick评分没有发现差异。5年测量显示，C组上颌弓形态最好（p=0.012）。最初的裂隙严重程度不影响上颌骨生长，但永久侧切牙的状况和III类家族史（分别为p=0.019和p=0.004）。在5岁的患者中，两阶段方法似乎对增长发展的危害最小。生长迟缓的预测因素包括没有侧切牙和III类家族史。
