Abstract：
Using the method of dominant lethal mutations, we assessed the frequency of the death of Drosophila melanogaster embryos under combined exposure to ionizing γ-radiation and non-ionizing pulsed magnetic field at various doses and modes of exposure. Mutagenic effect of combined exposure is antagonistic in nature. The antagonism is more pronounced when the following mode of exposure was used: exposure to non-ionizing pulsed magnetic field for 5 h followed by exposure to γ-radiation at doses of 3, 10, and 60 Gy. In case of reverse sequence of exposures, the antagonistic effect was statistically significant after exposure to γ-radiation at doses of 3 and 10 Gy, whereas at a dose of 20 Gy, a synergistic interaction was noted.
摘要：
使用显性致死突变的方法，我们评估了在不同剂量和暴露模式下联合暴露于电离γ辐射和非电离脉冲磁场的情况下,果蝇胚胎的死亡频率.联合暴露的诱变作用本质上是拮抗的。使用以下暴露方式时，拮抗作用更为明显：暴露于非电离脉冲磁场5小时，然后暴露于3、10和60Gy剂量的γ辐射。如果曝光顺序相反，在暴露于3和10Gy剂量的γ辐射后，拮抗作用具有统计学意义，而在20Gy的剂量下，注意到协同相互作用。
