PDF(Pubmed)
Abstract：
UNASSIGNED: Falls are a primary cause of injuries and hospitalization in older adults. It has been reported that cognitive impairments and dementia can increase fall risk in the older population; however, it remains unknown if fall risk differs among subgroups of dementia. This meta-analysis summarized previous studies reporting the annual fall risk of people with Alzheimer\'s disease (AD) or mild cognitive impairment (MCI) and compared the fall risk between these two groups of people with dementia.
UNASSIGNED: Thirty-five studies enrolling 7844 older adults with AD or MCI were included. The annual fall prevalence and average number of falls of the included studies were meta-analyzed and compared by random-effects models with inverse variance weights.
UNASSIGNED: The annual fall prevalence in people with AD (43.55%) was significantly higher than MCI (35.26%, p < 0.001). A χ2 test indicated that the pooled fall prevalence is significantly higher in people with AD than MCI χ2 = 158.403, p < 0.001). Additionally, the yearly average number of falls in AD was higher than in MCI (1.30 vs 0.77 falls/person).
UNASSIGNED: The results showed that older people with AD experience a higher annual fall prevalence with a larger number of falls than older adults with MCI. The results suggested that the fall risk measurements should be reported separately between people with AD and MCI. The findings could provide preliminary guidance for the identification of individuals with dementia who experience a high fall risk.
UNASSIGNED: Thirty-five studies enrolling 7844 older adults with AD or MCI were included. The annual fall prevalence and average number of falls of the included studies were meta-analyzed and compared by random-effects models with inverse variance weights.
UNASSIGNED: The annual fall prevalence in people with AD (43.55%) was significantly higher than MCI (35.26%, p < 0.001). A χ2 test indicated that the pooled fall prevalence is significantly higher in people with AD than MCI χ2 = 158.403, p < 0.001). Additionally, the yearly average number of falls in AD was higher than in MCI (1.30 vs 0.77 falls/person).
UNASSIGNED: The results showed that older people with AD experience a higher annual fall prevalence with a larger number of falls than older adults with MCI. The results suggested that the fall risk measurements should be reported separately between people with AD and MCI. The findings could provide preliminary guidance for the identification of individuals with dementia who experience a high fall risk.
摘要：
■跌倒是老年人受伤和住院的主要原因。据报道，认知障碍和痴呆症会增加老年人群的跌倒风险；然而，目前尚不清楚痴呆亚组的跌倒风险是否不同.这项荟萃分析总结了以前的研究报告阿尔茨海默病（AD）或轻度认知障碍（MCI）患者的年度跌倒风险，并比较了这两组痴呆症患者的跌倒风险。
■35项研究纳入7844名患有AD或MCI的老年人。对纳入研究的年跌倒患病率和平均跌倒次数进行荟萃分析，并通过具有逆方差权重的随机效应模型进行比较。
■AD患者的年跌倒患病率（43.55％）明显高于MCI（35.26％，p<0.001)。χ2检验表明，AD患者的合并跌倒患病率明显高于MCIχ2=158.403，p<0.001）。此外,AD患者的年平均跌倒次数高于MCI患者(1.30vs0.77次/人).
■结果显示，与MCI的老年人相比，患有AD的老年人的年跌倒患病率更高，跌倒次数更多。结果表明，跌倒风险测量应在AD和MCI患者之间单独报告。这些发现可以为识别跌倒风险高的痴呆症患者提供初步指导。
■35项研究纳入7844名患有AD或MCI的老年人。对纳入研究的年跌倒患病率和平均跌倒次数进行荟萃分析，并通过具有逆方差权重的随机效应模型进行比较。
■AD患者的年跌倒患病率（43.55％）明显高于MCI（35.26％，p<0.001)。χ2检验表明，AD患者的合并跌倒患病率明显高于MCIχ2=158.403，p<0.001）。此外,AD患者的年平均跌倒次数高于MCI患者(1.30vs0.77次/人).
■结果显示，与MCI的老年人相比，患有AD的老年人的年跌倒患病率更高，跌倒次数更多。结果表明，跌倒风险测量应在AD和MCI患者之间单独报告。这些发现可以为识别跌倒风险高的痴呆症患者提供初步指导。
