Abstract：
We report on a patient with delayed post-hypoxic leukoencephalopathy (DPHL) who showed akinetic mutism and gait disturbance, neural injuries that were demonstrated on diffusion tensor tractography (DTT). A patient was exposed to carbon monoxide (CO) and rapidly recovered; however, two weeks after onset, he began to show cognitive impairment and gait disturbance. At six weeks after CO exposure, he showed akinetic mutism and gait inability. DTT at 6-weeks post-exposure showed discontinuations in neural connectivities of the caudate nucleus to the medial prefrontal and orbitofrontal cortex in both hemispheres. In addition, the corticoreticulospinal tract revealed severe thinning in both hemispheres.
摘要：
我们报道了一名患有迟发性缺氧后白质脑病（DPHL）的患者，该患者表现出运动障碍和步态障碍，在弥散张量纤维束造影（DTT）上显示的神经损伤。一名患者暴露于一氧化碳（CO）并迅速康复；然而，发病两周后，他开始表现出认知障碍和步态障碍。接触一氧化碳后六周，他表现出运动障碍和步态障碍。暴露后6周的DTT显示，两个半球的尾状核与内侧前额叶和眶额皮质的神经连接中断。此外,皮质网状脊髓束显示两个半球严重变薄。
