Abstract：
Atopic dermatitis is a chronic dermatologic condition requiring extended treatment times with topical application of medications. While atopic dermatitis treatments can be highly effective when used as directed, oftentimes patients do not respond as expected, raising concern for nonadherence versus nonresponse. This chapter aims to describe what is currently known about adherence in atopic dermatitis and to discuss strategies to improve adherence in order to improve treatment outcomes. Whether intentional or unintentional, nonadherence to treatment can limit patient outcomes of this disease for a variety of reasons. These include frustration with medication efficacy, inconvenience, and fear of side effects. Other factors include forgetfulness, financial burden of treatment, lack of trust in the physician, dislike of prescribed medication, or lack of understanding of disease or treatment. Several interventions have been studied with the aim of improving adherence in atopic dermatitis-such as educational workshops for patients and caregivers, earlier follow-up visits, and text messages reminders-however, these are often limited by sample size and power. Further research is needed to study both specific patterns of nonadherence in atopic dermatitis, as well as methods to improve them.
摘要：
特应性皮炎是一种慢性皮肤病，需要延长治疗时间并局部应用药物。虽然特应性皮炎治疗在按指示使用时可以非常有效，通常患者没有预期的反应，提高对无依从性和无反应的关注。本章旨在描述目前已知的特应性皮炎的依从性，并讨论改善依从性以改善治疗结果的策略。无论是有意还是无意，由于多种原因,不坚持治疗会限制患者的预后.这些包括对药物疗效的挫败感，不便,和对副作用的恐惧。其他因素包括健忘，治疗的经济负担，对医生缺乏信任，不喜欢处方药，或对疾病或治疗缺乏了解。已经研究了几种干预措施，旨在提高特应性皮炎的依从性，例如针对患者和护理人员的教育研讨会，较早的后续访问，和短信提醒——然而，这些通常受到样本量和功率的限制。需要进一步的研究来研究特应性皮炎中两种特定的非依从性模式，以及改进它们的方法。
