METHODS: A 76-year-old male, known case of hepatitis B, diabetes, and hypertension, presented to the emergency department complaining of spitting blood and dysphagia. Imaging showed a heterogeneous enlarged left tonsil with hyperemia of the mucosa, and air foci. Biopsy with excisional biopsy confirmed the diagnosis of PLGA. The patient underwent completion tonsillectomy and selective neck dissection which yielded tonsillar tissue with underlying PLGA, and reactive lymph nodes with no malignant tissue respectively, margins were negative for malignancy.
UNASSIGNED: Polymorphous low-grade adenocarcinoma is a rare lesion with clinical behavior resembling that of a benign neoplasm. Predominantly occurring in the oral cavity, especially on the hard palate, buccal mucosa, and retromolar region, with fewer cases in the upper lip. Occurrence in the nasopharynx and oropharynx is rare. PLGA presents as painless slow-growing masses, typically in females aged 50-60. Local excision with careful margin evaluation is the preferred treatment, with good prognosis compared to other carcinomas.
CONCLUSIONS: PLGA is rare, with limited reported case from around the world. It is mostly seen in adults between their fifth and sixth decades with female predominance. PLGA is diagnosed using imaging, immunohistochemistry. Owing to the limited cases there is no standard approach to treating PLGA. However, most cases are managed with local excision and showed an excellent response in terms of tumor nonrecurrence.
方法:一名76岁男性,已知的乙型肝炎病例,糖尿病,和高血压,被送到急诊科,抱怨吐血和吞咽困难。影像学显示左侧扁桃体异型增大伴粘膜充血,和空气焦点。活检切除活检证实了PLGA的诊断。患者接受了完整的扁桃体切除术和选择性颈清扫术,产生了带有PLGA的扁桃体组织,和无恶性组织的反应性淋巴结,切缘为恶性肿瘤阴性.
■多形性低度恶性腺癌是一种罕见的病变,其临床行为类似于良性肿瘤。主要发生在口腔中,尤其是在硬腭上,颊粘膜,和后磨牙区,上唇的病例较少。发生在鼻咽和口咽是罕见的。PLGA表现为无痛缓慢增长的肿块,通常在50-60岁的女性中。局部切除并仔细评估切缘是首选治疗方法,与其他癌症相比预后良好。
结论:PLGA很少见,来自世界各地的报道病例有限。它主要见于年龄在五到六十年之间的成年人中,女性占主导地位。PLGA通过成像诊断,免疫组织化学。由于病例有限,没有治疗PLGA的标准方法。然而,大多数病例采用局部切除治疗,在肿瘤无复发方面表现出优异的疗效.