PDF(Pubmed)
Abstract：
UNASSIGNED: Prompt identification and management of anti-N-methyl-D-aspartate receptor encephalitis in young patients with acute psychiatric symptoms, seizures, and neurological deficits are crucial. Timely immunomodulatory therapy is essential for positive outcomes and minimizing long-term complications. High suspicion for this rare disorder is necessary for timely diagnosis and optimal care.
UNASSIGNED: Anti-N-methyl-D-aspartate (NMDA) receptor encephalitis is characterized by the presence of antibodies against the NMDA receptor, a crucial component of synaptic signaling. This autoimmune disorder often manifests with psychiatric symptoms, seizures, and neurological deficits. Early diagnosis is essential, as delayed treatment can result in severe complications. In this case, the patient received corticosteroids and intravenous immunoglobulin (IVIG), leading to a successful recovery with no lingering neurological abnormalities. The prompt initiation of treatment highlights the importance of recognizing this condition early. Anti-NMDA receptor encephalitis is a rare autoimmune disorder that presents with a range of neurological symptoms. In this case report, we highlight the significance of early recognition and treatment by discussing the emergency room visit of a 23-year-old woman who presented with acute-onset agitation, disorientation, and seizures. A 23-year-old woman, presented to the emergency room with acute-onset agitation, disorientation, and seizures. Magnetic resonance imaging (MRI) scans revealed temporal lobe signal alterations and electroencephalogram (EEG) showed widespread activity slowing. Importantly, anti-NMDA receptor antibodies were detected in both serum and cerebrospinal fluid, confirming the diagnosis of anti-NMDA receptor encephalitis. This case report underscores the significance of understanding the presentation, diagnosis, and treatment of anti-NMDA receptor encephalitis. Timely recognition and intervention are crucial for achieving favorable outcomes in patients with this rare but clinically important autoimmune disorder. Increased awareness among healthcare professionals is essential to ensure early diagnosis and prompt initiation of appropriate treatment strategies.
UNASSIGNED: Anti-N-methyl-D-aspartate (NMDA) receptor encephalitis is characterized by the presence of antibodies against the NMDA receptor, a crucial component of synaptic signaling. This autoimmune disorder often manifests with psychiatric symptoms, seizures, and neurological deficits. Early diagnosis is essential, as delayed treatment can result in severe complications. In this case, the patient received corticosteroids and intravenous immunoglobulin (IVIG), leading to a successful recovery with no lingering neurological abnormalities. The prompt initiation of treatment highlights the importance of recognizing this condition early. Anti-NMDA receptor encephalitis is a rare autoimmune disorder that presents with a range of neurological symptoms. In this case report, we highlight the significance of early recognition and treatment by discussing the emergency room visit of a 23-year-old woman who presented with acute-onset agitation, disorientation, and seizures. A 23-year-old woman, presented to the emergency room with acute-onset agitation, disorientation, and seizures. Magnetic resonance imaging (MRI) scans revealed temporal lobe signal alterations and electroencephalogram (EEG) showed widespread activity slowing. Importantly, anti-NMDA receptor antibodies were detected in both serum and cerebrospinal fluid, confirming the diagnosis of anti-NMDA receptor encephalitis. This case report underscores the significance of understanding the presentation, diagnosis, and treatment of anti-NMDA receptor encephalitis. Timely recognition and intervention are crucial for achieving favorable outcomes in patients with this rare but clinically important autoimmune disorder. Increased awareness among healthcare professionals is essential to ensure early diagnosis and prompt initiation of appropriate treatment strategies.
摘要：
■在有急性精神症状的年轻患者中迅速识别和治疗抗N-甲基-D-天冬氨酸受体脑炎，癫痫发作,神经缺陷至关重要。及时的免疫调节治疗对于积极的结果和减少长期并发症至关重要。高度怀疑这种罕见的疾病对于及时诊断和最佳护理是必要的。
■抗N-甲基-D-天冬氨酸（NMDA）受体脑炎的特征是存在抗NMDA受体的抗体，突触信号的重要组成部分。这种自身免疫性疾病通常表现为精神症状，癫痫发作,和神经缺陷。早期诊断至关重要，延迟治疗会导致严重的并发症。在这种情况下,患者接受了皮质类固醇和静脉注射免疫球蛋白（IVIG），导致成功的恢复，没有缠绵的神经异常。迅速开始治疗突出了早期认识到这种情况的重要性。抗NMDA受体脑炎是一种罕见的自身免疫性疾病，表现出一系列神经系统症状。在这个案例报告中,我们通过讨论一名23岁女性急性发作性躁动的急诊室就诊，强调早期识别和治疗的重要性，迷失方向，和癫痫发作。一个23岁的女人,急性发作性躁动被送到急诊室，迷失方向，和癫痫发作。磁共振成像（MRI）扫描显示颞叶信号改变，脑电图（EEG）显示广泛的活动减慢。重要的是,在血清和脑脊液中检测到抗NMDA受体抗体，确认抗NMDA受体脑炎的诊断。本案例报告强调了理解演示文稿的重要性，诊断,和抗NMDA受体脑炎的治疗。及时的识别和干预对于在这种罕见但临床上重要的自身免疫性疾病患者中获得有利的结果至关重要。提高医疗保健专业人员的认识对于确保早期诊断和及时启动适当的治疗策略至关重要。
■抗N-甲基-D-天冬氨酸（NMDA）受体脑炎的特征是存在抗NMDA受体的抗体，突触信号的重要组成部分。这种自身免疫性疾病通常表现为精神症状，癫痫发作,和神经缺陷。早期诊断至关重要，延迟治疗会导致严重的并发症。在这种情况下,患者接受了皮质类固醇和静脉注射免疫球蛋白（IVIG），导致成功的恢复，没有缠绵的神经异常。迅速开始治疗突出了早期认识到这种情况的重要性。抗NMDA受体脑炎是一种罕见的自身免疫性疾病，表现出一系列神经系统症状。在这个案例报告中,我们通过讨论一名23岁女性急性发作性躁动的急诊室就诊，强调早期识别和治疗的重要性，迷失方向，和癫痫发作。一个23岁的女人,急性发作性躁动被送到急诊室，迷失方向，和癫痫发作。磁共振成像（MRI）扫描显示颞叶信号改变，脑电图（EEG）显示广泛的活动减慢。重要的是,在血清和脑脊液中检测到抗NMDA受体抗体，确认抗NMDA受体脑炎的诊断。本案例报告强调了理解演示文稿的重要性，诊断,和抗NMDA受体脑炎的治疗。及时的识别和干预对于在这种罕见但临床上重要的自身免疫性疾病患者中获得有利的结果至关重要。提高医疗保健专业人员的认识对于确保早期诊断和及时启动适当的治疗策略至关重要。
