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Abstract：
Periodontal disease is the most common type of oral disease. Periodontal bone defect is the clinical outcome of advanced periodontal disease, which seriously affects the quality of life of patients. Promoting periodontal tissue regeneration and repairing periodontal bone defects is the ultimate treatment goal for periodontal disease, but the means and methods are very limited. Hydrogels are a class of highly hydrophilic polymer networks, and their good biocompatibility has made them a popular research material in the field of oral medicine in recent years. This paper reviews the current mainstream types and characteristics of hydrogels, and summarizes the relevant basic research on hydrogels in promoting periodontal tissue regeneration and bone defect repair in recent years. The possible mechanisms of action and efficacy evaluation are discussed in depth, and the application prospects are also discussed.
摘要：
牙周病是最常见的口腔疾病。牙周骨缺损是牙周病晚期的临床转归,严重影响患者的生活质量。促进牙周组织再生,修复牙周骨缺损是牙周病的最终治疗目标,但是手段和方法非常有限。水凝胶是一类高度亲水的聚合物网络，良好的生物相容性使其成为近年来口腔医学领域的热门研究材料。本文综述了目前主流的水凝胶的种类和特点,综述了近年来水凝胶促进牙周组织再生和骨缺损修复的相关基础研究。深入讨论了可能的作用机制和疗效评估，并对其应用前景进行了讨论。
