PDF(Pubmed)
Abstract：
OBJECTIVE: To present a case report of sinonasal glomangiopericytoma (GPC) in a female patient in her thirties and to highlight the importance of collecting pathology specimens even in routine sinus surgery cases.
METHODS: A case report detailing the diagnosis of GPC in a female in her thirties, including her initial presentation, treatment, and follow-up, along with a brief review of the literature.
RESULTS: Pathology of the collected specimen revealed sinonasal GPC along with chronic rhinosinusitis. Immunohistochemistry was positive for SMA, beta-catenin, and cyclin D1; and negative for STAT6, ERG, pankeratin, SOX10, and S100.
CONCLUSIONS: This diagnosis expands the knowledge around the demographic profile of GPC patients. GPC should be included in the differential diagnosis of sinonasal masses, even in younger patients. The case highlights the importance of collecting the entire pathology specimen in all cases, even of ones that seem routine and benign.
METHODS: A case report detailing the diagnosis of GPC in a female in her thirties, including her initial presentation, treatment, and follow-up, along with a brief review of the literature.
RESULTS: Pathology of the collected specimen revealed sinonasal GPC along with chronic rhinosinusitis. Immunohistochemistry was positive for SMA, beta-catenin, and cyclin D1; and negative for STAT6, ERG, pankeratin, SOX10, and S100.
CONCLUSIONS: This diagnosis expands the knowledge around the demographic profile of GPC patients. GPC should be included in the differential diagnosis of sinonasal masses, even in younger patients. The case highlights the importance of collecting the entire pathology specimen in all cases, even of ones that seem routine and benign.
摘要：
目的：介绍一例30多岁女性患者的鼻窦血管外皮细胞瘤（GPC）的病例报告，并强调即使在常规鼻窦手术中也要收集病理标本。
方法：一个病例报告，详述了一名30多岁的女性的GPC诊断，包括她最初的演讲,治疗,和后续行动，以及对文献的简要回顾。
结果：收集的标本病理显示鼻窦GPC和慢性鼻-鼻窦炎。免疫组织化学显示SMA阳性，β-catenin,和细胞周期蛋白D1；STAT6、ERG阴性，pankeratin,SOX10和S100。
结论：该诊断扩展了GPC患者人口统计学特征的知识。鼻窦肿块的鉴别诊断应包括GPC，即使是年轻患者。该病例强调了在所有病例中收集整个病理标本的重要性，甚至那些看起来常规和良性的。
方法：一个病例报告，详述了一名30多岁的女性的GPC诊断，包括她最初的演讲,治疗,和后续行动，以及对文献的简要回顾。
结果：收集的标本病理显示鼻窦GPC和慢性鼻-鼻窦炎。免疫组织化学显示SMA阳性，β-catenin,和细胞周期蛋白D1；STAT6、ERG阴性，pankeratin,SOX10和S100。
结论：该诊断扩展了GPC患者人口统计学特征的知识。鼻窦肿块的鉴别诊断应包括GPC，即使是年轻患者。该病例强调了在所有病例中收集整个病理标本的重要性，甚至那些看起来常规和良性的。
