Abstract：
Objectives: The Indian Registry on Current Patient Profiles and Treatment Trends in Hypertension (Record) evaluated the current trends and outcomes related to hypertension (HTN) management at 3, 6, 12, and 24 months in India. This study highlights and evaluates the outcomes and trends noted at 24 months. Materials and methods: The detailed study methodology is provided in the earlier publication (interim analysis at 12 months). Aspects such as changes in the quality of life (QOL), percentage of patients reaching target blood pressure (BP), treatment pattern among patients with comorbid conditions, and difference in treatment patterns between public and private healthcare settings, at 24 months, were evaluated in the current study. Results: The study population included 2,000 patients (55.7% males) with a mean age of 54.45 years. Telmisartan (43.7%) and amlodipine + telmisartan (16.4%) were the most prescribed monotherapy and combination therapy among patients with newly diagnosed HTN. A significant decrease in both systolic BP (SBP) and diastolic BP (DBP) was noted in the overall patient population at 24 months (p < 0.001). The mean change in SBP and DBP was slightly higher at 24 months compared to 12 months. This was more evident among patients on combination therapy. A significant improvement in QOL was noted at 24 months. Conclusion: Treatment strategies in HTN management are changing and are associated with effective HTN control and improvements in QOL. However, there is a further need for improved awareness regarding the optimal usage of combination therapy for better management of uncontrolled HTN. How to cite this article: Rajadhyaksha GC, Reddy H, Singh AK, et al. The Indian REgistry on Current Patient PrOfiles and TReatment TrenDs in Hypertension (RECORD): Final Outcomes of the Real-World Observational Study. J Assoc Physicians India 2023;71(11):43-49.
摘要：
目标：印度当前高血压患者概况和治疗趋势注册（记录）评估了印度3、6、12和24个月与高血压（HTN）管理相关的当前趋势和结果。这项研究强调并评估了24个月时注意到的结果和趋势。材料和方法：在较早的出版物中提供了详细的研究方法（12个月的中期分析）。如生活质量(QOL)的变化，达到目标血压（BP）的患者百分比，共病患者的治疗模式，以及公立和私立医疗机构之间治疗模式的差异，24个月时,在当前的研究中进行了评估。结果：研究人群包括2,000名患者（55.7％为男性），平均年龄为54.45岁。在新诊断的HTN患者中，替米沙坦（43.7％）和氨氯地平替米沙坦（16.4％）是最常用的单一疗法和联合疗法。在24个月时，所有患者的收缩压（SBP）和舒张压（DBP）均显著下降（p<0.001）。与12个月相比，24个月时SBP和DBP的平均变化略高。这在接受联合治疗的患者中更为明显。在24个月时注意到QOL的显著改善。结论：HTN管理中的治疗策略正在发生变化，并且与有效的HTN控制和QOL的改善有关。然而,进一步需要提高对联合治疗的最佳使用的认识,以更好地管理不受控制的HTN.如何引用这篇文章:RajadhyakshaGC,ReddyH,SinghAK,etal.印度关于高血压患者当前治疗和治疗趋势的记录（记录）：真实世界观察研究的最终结果。JAssoc印度医师2023；71(11)：43-49。
