PDF(Pubmed)
Abstract：
Although the application of magnetic compression anastomosis is becoming increasingly widespread, the magnets used in earlier studies were mostly in the shape of a whole ring. Hence, a deformable self-assembled magnetic anastomosis ring (DSAMAR) was designed in this study for gastrointestinal anastomosis. Furthermore, its feasibility was studied using a beagle model. The designed DSAMAR comprised 10 trapezoidal magnetic units. Twelve beagles were used as animal models, and DSAMARs were inserted into the stomach and colon through the mouth and anus, respectively, via endoscopy to achieve gastrocolic magnamosis. Surgical time, number of failed deformations, survival rate of the animals, and the time of magnet discharge were documented. A month later, specimens of the anastomosis were obtained and observed with the naked eye as well as microscopically. In the gastrocolic anastomosis of the 12 beagles, the procedure took 65-120 min. Although a deformation failure occurred during the operation in one of the beagles, it was successful after repositioning. The anastomosis was formed after the magnet fell off 12-18 days after the operation. Naked eye and microscopic observations revealed that the anastomotic specimens obtained 1 month later were well-formed, smooth, and flat. DSAMAR is thus feasible for gastrointestinal anastomosis under full endoscopy via the natural orifice.
摘要：
尽管磁压缩吻合术的应用日益广泛,早期研究中使用的磁铁大多是整个环的形状。因此，本研究设计了一种可变形的自组装磁性吻合环(DSAMAR),用于胃肠吻合.此外，使用beagle模型研究了其可行性。设计的DSAMAR包括10个梯形磁性单元。12只小猎犬被用作动物模型，DSAMAR通过口腔和肛门插入胃和结肠，分别,通过内窥镜检查来实现胃绞痛。手术时间,失败变形的数量，动物的存活率，并记录了磁铁放电的时间。一个月后,获取吻合标本，并用肉眼和显微镜观察。在12只小猎犬的胃结肠吻合术中，该过程需要65-120分钟。尽管其中一只小猎犬在手术期间发生了变形故障，重新定位后成功了。在手术后12-18天磁体脱落后形成吻合。裸眼和显微镜观察显示，1个月后获得的吻合标本形状良好，光滑,和平坦的。因此，DSAMAR通过自然孔口在全内窥镜下进行胃肠道吻合是可行的。
