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Abstract：
Cardiometabolic multimorbidity (CM), defined as the coexistence of two or three cardiometabolic disorders, is one of the most common and deleterious multimorbidities. This study aimed to investigate the association of Clínica Universidad de Navarra-Body Adiposity Estimator (CUN-BAE), body mass index (BMI), waist circumference (WC), and waist-to-height ratio (WHtR) with the prevalence of CM. The data were obtained from the 2021 health checkup database for residents of the Electronic Health Management Center in Xinzheng, Henan Province, China. 81,532 participants aged ≥ 60 years were included in this study. Logistic regression models were used to estimate the odd ratios (ORs) and 95% confidence intervals (CIs) for CUN-BAE, BMI, WC, and WHtR in CM. The area under the receiver operating characteristic curve (AUC) was used to compare the discriminatory ability of different anthropometric indicators for CM. The multivariable-adjusted ORs (95% CIs) (per 1 SD increase) of CM were 1.799 (1.710-1.893) for CUN-BAE, 1.329 (1.295-1.364) for BMI, 1.343 (1.308-1.378) for WC, and 1.314 (1.280-1.349) for WHtR, respectively. Compared with BMI, WC and WHtR, CUN-BAE had the highest AUC in both males and females (AUC: 0.642; 95% CI 0.630-0.653 for males, AUC: 0.614; 95% CI 0.630-0.653 for females). CUN-BAE may be a better measure of the adverse effect of adiposity on the prevalence of CM than BMI, WC, and WHtR.
摘要：
心脏代谢多发病率（CM），定义为两种或三种心脏代谢紊乱并存，是最常见和有害的多重性疾病之一。本研究旨在调查纳瓦拉克莱尼卡大学-身体脂肪估计器（CUN-BAE）的关联，体重指数（BMI），腰围（WC），腰围身高比（WHtR）与CM的患病率。数据来源于新郑市电子健康管理中心2021年居民健康体检数据库，河南省,中国。81,532名年龄≥60岁的参与者被纳入本研究。使用Logistic回归模型估计CUN-BAE的奇数比(ORs)和95%置信区间(CIs)。BMI,WC,和WHtR在CM。受试者工作特征曲线下面积（AUC）用于比较不同人体测量指标对CM的判别能力。CUN-BAE的CM多变量调整OR（95％CIs）（每增加1SD）为1.799（1.710-1.893），BMI为1.329（1.295-1.364），WC为1.343（1.308-1.378），WHtR为1.314(1.280-1.349)，分别。与BMI相比，WC和WHtR,CUN-BAE在男性和女性中的AUC最高（AUC：0.642；男性的95％CI0.630-0.653，AUC：0.614；女性95%CI0.630-0.653）。CUN-BAE可能比BMI更好地衡量肥胖对CM患病率的不利影响，WC,和WHTR。
