BRAF 和 MEK 抑制剂可能诱发 BRAF V600E 阳性肺腺癌大血管血管炎.
关键词: Lung cancer (oncology) Malignant disease and immunosuppression Vasculitis
Mesh : Humans Proto-Oncogene Proteins B-raf / antagonists & inhibitors genetics Female Pyridones / adverse effects therapeutic use Pyrimidinones / therapeutic use adverse effects Lung Neoplasms / drug therapy Aged Adenocarcinoma of Lung / drug therapy Imidazoles / adverse effects therapeutic use Oximes / adverse effects therapeutic use Vasculitis / chemically induced Protein Kinase Inhibitors / adverse effects therapeutic use Prednisolone / therapeutic use Methotrexate / therapeutic use adverse effects Antineoplastic Combined Chemotherapy Protocols / adverse effects therapeutic use
来 源: DOI:10.1136/bcr-2023-255958 PDF(Pubmed)