Abstract：
Cancer is a leading cause of death in both China and developed countries due to its high incidence and low cure rate. Immune function is closely linked to the development and progression of tumors. Platelets, which are primarily known for their role in hemostasis, also play a crucial part in the spread and progression of tumors through their interaction with the immune microenvironment. The impact of platelets on tumor growth and metastasis depends on the type of cancer and treatment method used. This article provides an overview of the relationship between platelets and the immune microenvironment, highlighting how platelets can either protect or harm the immune response and cancer immune escape. We also explore the potential of available platelet-targeting strategies for tumor immunotherapy, as well as the promise of new platelet-targeted tumor therapy methods through further research.
摘要：
癌症发病率高、治愈率低，是我国和发达国家的主要死因。免疫功能与肿瘤的发展和进展密切相关。血小板,主要以止血作用而闻名，通过与免疫微环境的相互作用，在肿瘤的扩散和进展中也起着至关重要的作用。血小板对肿瘤生长和转移的影响取决于癌症的类型和使用的治疗方法。本文概述了血小板与免疫微环境的关系,强调血小板如何保护或损害免疫反应和癌症免疫逃逸。我们还探讨了肿瘤免疫治疗可用的血小板靶向策略的潜力，以及通过进一步研究新的血小板靶向肿瘤治疗方法的前景。
