Abstract：
In this study, a QuEChERS method based on citrate was developed and utilized for the analysis of twelve neonicotinoid pesticides in fresh red chilies, fresh green chilies, and dried chilies, coupled with ultra-high performance liquid chromatography quadrupole time of flight mass spectrometry (UPLC-Q-TOF/MS). In the sample preparation, acetonitrile containing 1% formic acid was used as the extraction solvent. Anhydrous sodium sulfate replaced the traditional anhydrous magnesium sulfate for water removal, effectively eliminating the issues of salt caking. Graphitized carbon black, octadecyl silica, and primary secondary amine were used as cleaning agents. The method showed good sensitivity, with the limits of quantification below 0.03 mg/kg for fresh chilies and below 0.15 mg/kg for dried chilies. Values of matrix effects ranged from -19.5% to 8.4%, and the recovery was 86.9% - 105.2%. The analytical method provided an effective tool for the high throughput detection of neonicotinoid pesticide residues in multiple chili matrices.
摘要：
在这项研究中,开发了一种基于柠檬酸盐的QuEChERS方法，并用于分析新鲜红辣椒中的十二种新烟碱类农药，新鲜的绿色辣椒，干辣椒，超高效液相色谱-四极杆飞行时间质谱(UPLC-Q-TOF/MS)。在样品制备中，使用含1%甲酸的乙腈作为萃取溶剂。无水硫酸钠取代传统的无水硫酸镁用于除水，有效消除盐结块的问题。石墨化炭黑,十八烷基二氧化硅，和伯仲胺被用作清洁剂。该方法具有良好的灵敏度,新鲜辣椒的定量限低于0.03mg/kg，干辣椒的定量限低于0.15mg/kg。矩阵效应的值范围从-19.5%到8.4%，回收率为86.9%-105.2%。该分析方法为多种辣椒基质中新烟碱类农药残留的高通量检测提供了有效工具。
