关键词: overview of systematic reviews post-stroke cognitive impairment radar plot repetitive transcranial magnetic stimulation stroke

来  源:   DOI:10.3389/fneur.2024.1378731   PDF(Pubmed)

Abstract:
UNASSIGNED: The reliability of clinical evidence depends on high-quality meta-analyses/ systematic reviews (MAs/SRs). However, there has been no assessment of the quality of MAs/SRs for repetitive transcranial magnetic stimulation (rTMS) in post-stroke cognitive impairment (PSCI), both nationally and internationally. This article seeks to use radar plotting to visually present the quality of MAs/SRs on rTMS for improving cognitive function in PSCI, aiming to offer an intuitive foundation for clinical research.
UNASSIGNED: Eight Chinese or English databases were systematically searched to collect comprehensive literature, and the retrieval time ranged from inception to 26 March 2024. Literature ranking was calculated using six dimensions: publication year, design type, AMSTAR-2 score, PRISMA score, publication bias, and homogeneity. Finally, radar plots were drafted to present a multivariate literature evaluation. The GRADE tool assessed the strength of evidence for the outcome indicators included in the MAs/SRs.
UNASSIGNED: The 17 articles included had average scores of 12.29, 17, 9.88, 9.71, 12.88, and 12.76 for each dimension. The radar plot showed that an article published in 2023 had the highest rank and a large radar plot area, while an article published in 2021 had the lowest rank and a small radar plot area. The GRADE tool evaluation revealed that 51 pieces of evidence were of very low quality, 67 were of low quality, 12 were of moderate quality, and only one was of high quality.
UNASSIGNED: The average rank score of literature ranged from 8.50 to 17, with higher rankings indicating greater significance in literature reference. Variations in literature quality were attributed to inadequate study planning, irregular literature search and screening, insufficient description of inclusion criteria for studies, and inadequate consideration of bias risk in the included studies. Most MAs/SRs indicated that rTMS was more effective than the control group in enhancing the global cognitive function and activities of daily living in PSCI patients. However, the overall quality of the literature was generally low and needs validation from future high-quality evidence.Systematic review registration:https://www.crd.york.ac.uk/prospero/, identifier CRD42023491280.
摘要:
临床证据的可靠性取决于高质量的荟萃分析/系统综述(MA/SRs)。然而,尚未评估卒中后认知障碍(PSCI)中重复经颅磁刺激(rTMS)的MA/SR质量,国内和国际。本文试图利用雷达绘图直观地呈现rTMS上的MA/SR质量,以改善PSCI中的认知功能,旨在为临床研究提供直观的基础。
系统地检索了八个中文或英文数据库,以收集全面的文献,检索时间从开始到2024年3月26日。文献排名使用六个维度计算:出版年份,设计类型,AMSTAR-2得分,PRISMA得分,出版偏见,和同质性。最后,起草了雷达图,以提供多元文献评估。等级工具评估了MAS/SRs中包含的结果指标的证据强度。
所包含的17篇文章的平均得分分别为12.29、17、9.88、9.71、12.88和12.76。雷达图显示,2023年发表的一篇文章排名最高,雷达图面积很大,而2021年发表的一篇文章的排名最低,雷达图面积很小。等级工具评估显示,51份证据质量非常低,67个质量低,12个中等质量,只有一个是高质量的。
文献的平均等级得分在8.50至17之间,较高的等级表示在文献参考中的意义更大。文献质量的变化归因于研究规划不足,不规则的文献检索和筛选,对研究的纳入标准描述不足,纳入研究对偏倚风险的考虑不足。大多数MAs/SRs表明rTMS在增强PSCI患者的整体认知功能和日常生活活动方面比对照组更有效。然而,文献的总体质量普遍较低,需要从未来的高质量证据中进行验证.系统审查注册:https://www。crd.约克。AC.英国/普华永道/,标识符CRD42023491280。
公众号