关键词: gastroenterology high igm hyper-reactive malarial splenomegaly syndrome (hmss) lymphocytosis malaria tropical splenomegaly syndrome (tss)

来  源:   DOI:10.7759/cureus.72   PDF(Pubmed)

Abstract:
Hyper-reactive malarial splenomegaly syndrome (HMSS) is a massive enlargement of the spleen due to an exaggerated immune response to repeated attacks of malaria.  Tropical splenomegaly syndrome (TSS) is the most frequent cause of massive tropical splenomegaly in malarious areas [1-2].  It is seen more commonly among residents of endemic areas of malaria.  It occurs mainly in tropical Africa, but also in parts of Vietnam, New Guinea, India, Srilanka, Thailand, Indonesia, South America, and the Middle East. TSS is characterized by massive splenomegaly, hepatomegaly, marked elevations in levels of serum IgM, and malaria antibody.
摘要:
高反应性疟疾脾肿大综合征(HMSS)是由于对疟疾反复发作的过度免疫反应而引起的脾脏大量增大。热带脾肿大综合征(TSS)是疟疾地区热带脾肿大的最常见原因[1-2]。在疟疾流行地区的居民中更常见。它主要发生在热带非洲,而且在越南的部分地区,几内亚,印度,斯里兰卡,泰国,印度尼西亚,南美洲,和中东。TSS的特征是大量脾肿大,肝肿大,血清IgM水平显著升高,和疟疾抗体。
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