METHODS: Patients treated for tongue cancer at our hospital between 2018 and 2022 were categorized by partial, hemi, or subtotal/total glossectomy. Assessments included swallowing function (RSST), articulation (Oral Diadochokinesis (ODK)), mastication, tongue pressure, and oral moisture. QoL was measured using the Oral Health Impact Profile-14 (OHIP-14). Differences within parameters were assessed using Kruskal-Wallis tests, and between-group comparisons via Mann-Whitney U tests. Spearman\'s correlation analysis examined parameter relationship.
RESULTS: 35 patients were evaluated. Significant differences were found in ODK [ta] (p = 0.015), [ka] (p = 0.0006), tongue pressure (p = 0.0001), moisture levels (p = 0.031), OHIP-14 domains: physical disability (p = 0.014) and social disability (p = 0.046). ODK [ta] (PG: 5.95, HG: 5.38, TG: 4.03 times), [ka] (PG: 5.56, HG: 4.78, TG: 3.23 times), and tongue pressure (PG: 32.9, HG: 21.2, TG: 10.3 mmHg) decreased with glossectomy extent, while physical (PG: 0.27, HG: 2.38, TG: 2.00) and social disability (PG: 0.18, HG: 0.94, TG: 1.43) worsened. A significant negative correlation was observed between tongue pressure and social disability (p = 0.013, r = -0.36).
CONCLUSIONS: Expanding resection significantly impacted postoperative oral function and QoL. Tongue pressure assessment may predict long-term social disability in patient QoL.
方法:2018年至2022年在我院接受舌癌治疗的患者按部分分类,hemi,或舌部次全/全切除术。评估包括吞咽功能(RSST),关节连接(口服关节运动(ODK)),咀嚼,舌头的压力,和口腔水分。使用口腔健康影响概况-14(OHIP-14)测量QoL。使用Kruskal-Wallis检验评估参数内的差异,通过Mann-WhitneyU检验进行组间比较。Spearman的相关分析检验了参数关系。
结果:对35例患者进行了评估。ODK[ta]存在显著差异(p=0.015),[ka](p=0.0006),舌压(p=0.0001),湿度水平(p=0.031),OHIP-14领域:身体残疾(p=0.014)和社会残疾(p=0.046)。ODK[ta](PG:5.95,HG:5.38,TG:4.03倍),[ka](PG:5.56,HG:4.78,TG:3.23倍),舌压(PG:32.9,HG:21.2,TG:10.3mmHg)随舌片切除程度降低,身体(PG:0.27,HG:2.38,TG:2.00)和社会残疾(PG:0.18,HG:0.94,TG:1.43)恶化。舌压与社会残疾呈显著负相关(p=0.013,r=-0.36)。
结论:扩大切除对术后口腔功能和生活质量有显著影响。舌压评估可以预测患者QoL的长期社会残疾。