Abstract：
BACKGROUND: The extent of surgical resection for tongue tumors is determined by tumor size, potentially affecting oral function and quality of life (QoL). However, the relationship between oral dysfunction and QoL decline due to glossectomy extent remains unexplored. Therefore, these correlations and their predictive value for postoperative QoL decline were elucidated.
METHODS: Patients treated for tongue cancer at our hospital between 2018 and 2022 were categorized by partial, hemi, or subtotal/total glossectomy. Assessments included swallowing function (RSST), articulation (Oral Diadochokinesis (ODK)), mastication, tongue pressure, and oral moisture. QoL was measured using the Oral Health Impact Profile-14 (OHIP-14). Differences within parameters were assessed using Kruskal-Wallis tests, and between-group comparisons via Mann-Whitney U tests. Spearman\'s correlation analysis examined parameter relationship.
RESULTS: 35 patients were evaluated. Significant differences were found in ODK [ta] (p = 0.015), [ka] (p = 0.0006), tongue pressure (p = 0.0001), moisture levels (p = 0.031), OHIP-14 domains: physical disability (p = 0.014) and social disability (p = 0.046). ODK [ta] (PG: 5.95, HG: 5.38, TG: 4.03 times), [ka] (PG: 5.56, HG: 4.78, TG: 3.23 times), and tongue pressure (PG: 32.9, HG: 21.2, TG: 10.3 mmHg) decreased with glossectomy extent, while physical (PG: 0.27, HG: 2.38, TG: 2.00) and social disability (PG: 0.18, HG: 0.94, TG: 1.43) worsened. A significant negative correlation was observed between tongue pressure and social disability (p = 0.013, r = -0.36).
CONCLUSIONS: Expanding resection significantly impacted postoperative oral function and QoL. Tongue pressure assessment may predict long-term social disability in patient QoL.
METHODS: Patients treated for tongue cancer at our hospital between 2018 and 2022 were categorized by partial, hemi, or subtotal/total glossectomy. Assessments included swallowing function (RSST), articulation (Oral Diadochokinesis (ODK)), mastication, tongue pressure, and oral moisture. QoL was measured using the Oral Health Impact Profile-14 (OHIP-14). Differences within parameters were assessed using Kruskal-Wallis tests, and between-group comparisons via Mann-Whitney U tests. Spearman\'s correlation analysis examined parameter relationship.
RESULTS: 35 patients were evaluated. Significant differences were found in ODK [ta] (p = 0.015), [ka] (p = 0.0006), tongue pressure (p = 0.0001), moisture levels (p = 0.031), OHIP-14 domains: physical disability (p = 0.014) and social disability (p = 0.046). ODK [ta] (PG: 5.95, HG: 5.38, TG: 4.03 times), [ka] (PG: 5.56, HG: 4.78, TG: 3.23 times), and tongue pressure (PG: 32.9, HG: 21.2, TG: 10.3 mmHg) decreased with glossectomy extent, while physical (PG: 0.27, HG: 2.38, TG: 2.00) and social disability (PG: 0.18, HG: 0.94, TG: 1.43) worsened. A significant negative correlation was observed between tongue pressure and social disability (p = 0.013, r = -0.36).
CONCLUSIONS: Expanding resection significantly impacted postoperative oral function and QoL. Tongue pressure assessment may predict long-term social disability in patient QoL.
摘要：
背景：手术切除舌肿瘤的范围取决于肿瘤的大小，可能影响口腔功能和生活质量(QoL)。然而,口腔功能障碍与舌片切除程度导致的QoL下降之间的关系仍未研究。因此,阐明了这些相关性及其对术后QoL下降的预测价值.
方法：2018年至2022年在我院接受舌癌治疗的患者按部分分类，hemi,或舌部次全/全切除术。评估包括吞咽功能（RSST），关节连接（口服关节运动（ODK）），咀嚼,舌头的压力,和口腔水分。使用口腔健康影响概况-14(OHIP-14)测量QoL。使用Kruskal-Wallis检验评估参数内的差异，通过Mann-WhitneyU检验进行组间比较。Spearman的相关分析检验了参数关系。
结果：对35例患者进行了评估。ODK[ta]存在显著差异(p=0.015)，[ka](p=0.0006)，舌压（p=0.0001），湿度水平（p=0.031），OHIP-14领域：身体残疾（p=0.014）和社会残疾（p=0.046）。ODK[ta](PG:5.95,HG:5.38,TG:4.03倍),[ka](PG:5.56,HG:4.78,TG:3.23倍),舌压(PG:32.9,HG:21.2,TG:10.3mmHg)随舌片切除程度降低,身体（PG：0.27，HG：2.38，TG：2.00）和社会残疾（PG：0.18，HG：0.94，TG：1.43）恶化。舌压与社会残疾呈显著负相关(p=0.013,r=-0.36)。
结论：扩大切除对术后口腔功能和生活质量有显著影响。舌压评估可以预测患者QoL的长期社会残疾。
方法：2018年至2022年在我院接受舌癌治疗的患者按部分分类，hemi,或舌部次全/全切除术。评估包括吞咽功能（RSST），关节连接（口服关节运动（ODK）），咀嚼,舌头的压力,和口腔水分。使用口腔健康影响概况-14(OHIP-14)测量QoL。使用Kruskal-Wallis检验评估参数内的差异，通过Mann-WhitneyU检验进行组间比较。Spearman的相关分析检验了参数关系。
结果：对35例患者进行了评估。ODK[ta]存在显著差异(p=0.015)，[ka](p=0.0006)，舌压（p=0.0001），湿度水平（p=0.031），OHIP-14领域：身体残疾（p=0.014）和社会残疾（p=0.046）。ODK[ta](PG:5.95,HG:5.38,TG:4.03倍),[ka](PG:5.56,HG:4.78,TG:3.23倍),舌压(PG:32.9,HG:21.2,TG:10.3mmHg)随舌片切除程度降低,身体（PG：0.27，HG：2.38，TG：2.00）和社会残疾（PG：0.18，HG：0.94，TG：1.43）恶化。舌压与社会残疾呈显著负相关(p=0.013,r=-0.36)。
结论：扩大切除对术后口腔功能和生活质量有显著影响。舌压评估可以预测患者QoL的长期社会残疾。
