Abstract：
In the realm of healthcare and the advancing field of medical sciences, the development of efficient drug delivery systems become an immense promise to cure several diseases. Despite considerable advancements in drug delivery systems, numerous challenges persist, necessitating further enhancements to optimize patient outcomes. Smart nano-carriers, for instance, 2D sheets nano-carriers are the recently emerging nanosheets that may garner attention for targeted delivery of bioactive compounds, drugs, and genes to kill cancer cells. Within these advancements, Ti3C2TX-MXene, characterized as a two-dimensional transition metal carbide, has surfaced as a prominent intelligent nanocarrier within nanomedicine. Its noteworthy characteristics facilitated it as an ideal nanocarrier for cancer therapy. In recent advancements in drug delivery research, Ti3C2TX-MXene 2D nanocarriers have been designed to release drugs in response to specific stimuli, guided by distinct physicochemical parameters. This review emphasized the multifaceted role of Ti3C2TX-MXene as a potential carrier for delivering poorly hydrophilic drugs to cancer cells, facilitated by various polymer coatings. Furthermore, beyond drug delivery, this smart nanocarrier demonstrates utility in photoacoustic imaging and photothermal therapy, further highlighting its significant role in cellular mechanisms.
摘要：
在医疗保健领域和医学科学的发展领域，高效药物递送系统的发展成为治愈多种疾病的巨大希望。尽管药物递送系统取得了相当大的进步，许多挑战依然存在，需要进一步增强以优化患者结果。智能纳米载体，例如,2D片纳米载体是最近出现的纳米片，可能会引起生物活性化合物靶向递送的关注，毒品,和杀死癌细胞的基因。在这些进步中，Ti3C2TX-MXene,特征为二维过渡金属碳化物，已经成为纳米医学中突出的智能纳米载体。其值得注意的特性使其成为癌症治疗的理想纳米载体。在药物递送研究的最新进展中，Ti3C2TX-MXene2D纳米载体被设计用于响应特定刺激释放药物，以不同的物理化学参数为指导。这篇综述强调了Ti3C2TX-MXene作为向癌细胞递送亲水性差的药物的潜在载体的多方面作用。通过各种聚合物涂层促进。此外，除了药物输送，这种智能纳米载体在光声成像和光热治疗中具有实用性，进一步强调其在细胞机制中的重要作用。
