PDF(Pubmed)
Abstract：
Pericardial mesothelioma (PM) is rare with only 200 cases recorded, and a post-mortem prevalence of <0.0022%. It is the third most common cardiac/pericardial tumour, behind angiosarcoma and rhabdomyosarcoma. PM incidence increases with age, typically incidentally diagnosed between 50 and 70 years, with a 3:1 male predominance. Occasional PM can cause chest pain, dyspnoea, cough and even dysphagia. PMs are often misdiagnosed with only 25% of cases being antemortem diagnoses. Unlike pleural mesothelioma, the link between asbestos exposure and malignancy is less convincing, with only 20% of cases having known exposure. 6 There are three histological types: epithelioid, fibrous (spindle cell), and biphasic (mixed). The average life-expectancy post diagnosis is 3-10 months. Due to the heterogeneity of the presentation and rarity there is no standardized management algorithm, and the diagnostic imaging or laboratory investigations are scarcely described. We are presenting one of the cases diagnosed in our unit here in the Gold Coast.
摘要：
心包间皮瘤（PM）是罕见的，只有200例记录，验尸率<0.0022%。它是第三常见的心脏/心包肿瘤，在血管肉瘤和横纹肌肉瘤后面.PM发病率随着年龄的增长而增加，通常在50到70岁之间偶然诊断，男性占3:1。偶尔PM会引起胸痛,呼吸困难,咳嗽甚至吞咽困难。PM经常被误诊，只有25％的病例是死前诊断。与胸膜间皮瘤不同，石棉暴露与恶性肿瘤之间的联系不太令人信服，只有20%的病例有已知的暴露。6有三种组织学类型：上皮样，纤维（梭形细胞），和双相（混合）。诊断后的平均预期寿命为3-10个月。由于呈现的异质性和稀有性，没有标准化的管理算法，几乎没有描述诊断成像或实验室检查。我们正在介绍黄金海岸我们单位诊断的一例病例。
