Abstract：
BACKGROUND: There is no consensus regarding age-related facial anatomical changes. In this study, aging-related changes in soft and hard cheek tissues were quantitatively analyzed using computed tomography.
METHODS: We performed a retrospective study of 90 Asian females who underwent facial computed tomography. Three-dimensional model of soft tissue in apple zone was reconstructed, and age-related changes in fat volume and pyriform aperture area were quantified using Mimics software.
RESULTS: The apple zone is an aesthetic unit of the infraorbital cheek, with soft tissue located between the lateral wall of the pyriform aperture and the zygomatic major muscle. The superficial fat volume significantly decreased with age (P < 0.05). In contrast, a significant decrease in total fat volume was only observed between the young and old groups (P < 0.05). In linear regression modeling, age was a significant predictor of pyriform aperture area (R2 = 0.194, P < 0.001).
CONCLUSIONS: These results suggest that superficial fat atrophy and bone remodeling in the cheek with age, and both of which combine to contribute to an aging facial appearance.
METHODS: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .
METHODS: We performed a retrospective study of 90 Asian females who underwent facial computed tomography. Three-dimensional model of soft tissue in apple zone was reconstructed, and age-related changes in fat volume and pyriform aperture area were quantified using Mimics software.
RESULTS: The apple zone is an aesthetic unit of the infraorbital cheek, with soft tissue located between the lateral wall of the pyriform aperture and the zygomatic major muscle. The superficial fat volume significantly decreased with age (P < 0.05). In contrast, a significant decrease in total fat volume was only observed between the young and old groups (P < 0.05). In linear regression modeling, age was a significant predictor of pyriform aperture area (R2 = 0.194, P < 0.001).
CONCLUSIONS: These results suggest that superficial fat atrophy and bone remodeling in the cheek with age, and both of which combine to contribute to an aging facial appearance.
METHODS: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .
摘要：
背景：关于与年龄相关的面部解剖结构变化尚无共识。在这项研究中,使用计算机断层扫描定量分析了软和硬脸颊组织中与衰老相关的变化。
方法：我们对90名接受面部计算机断层扫描的亚洲女性进行了回顾性研究。建立苹果区软组织三维模型,使用Mimics软件对与年龄相关的脂肪体积和梨形孔面积的变化进行定量。
结果：苹果区是眶下脸颊的美学单位，软组织位于梨状孔的侧壁和zu大肌之间。浅表脂肪体积随年龄增长而显著下降(P<0.05)。相比之下,仅在年轻组和老年组之间观察到总脂肪体积显著减少(P<0.05).在线性回归建模中，年龄是梨状孔面积的显著预测因子(R2=0.194,P<0.001).
结论：这些结果表明，随着年龄的增长，面颊表面脂肪萎缩和骨重建，两者结合起来有助于面部外观的老化。
方法：本期刊要求作者为每篇文章分配一定程度的证据。对于这些循证医学评级的完整描述，请参阅目录或在线作者说明www。springer.com/00266.
方法：我们对90名接受面部计算机断层扫描的亚洲女性进行了回顾性研究。建立苹果区软组织三维模型,使用Mimics软件对与年龄相关的脂肪体积和梨形孔面积的变化进行定量。
结果：苹果区是眶下脸颊的美学单位，软组织位于梨状孔的侧壁和zu大肌之间。浅表脂肪体积随年龄增长而显著下降(P<0.05)。相比之下,仅在年轻组和老年组之间观察到总脂肪体积显著减少(P<0.05).在线性回归建模中，年龄是梨状孔面积的显著预测因子(R2=0.194,P<0.001).
结论：这些结果表明，随着年龄的增长，面颊表面脂肪萎缩和骨重建，两者结合起来有助于面部外观的老化。
方法：本期刊要求作者为每篇文章分配一定程度的证据。对于这些循证医学评级的完整描述，请参阅目录或在线作者说明www。springer.com/00266.
