ASS1 通过调节 PHGDH 稳定性和从头丝氨酸合成抑制三阴性乳腺癌。
Mesh : Phosphoglycerate Dehydrogenase / metabolism genetics Serine / metabolism biosynthesis Humans Female Triple Negative Breast Neoplasms / metabolism pathology genetics Cell Proliferation Animals Argininosuccinate Synthase / metabolism genetics Cell Line, Tumor Mice, Nude Ubiquitination Mice Glycine / metabolism
来 源:
DOI:10.1038/s41419-024-06672-z
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