PDF(Pubmed)
Abstract：
UNASSIGNED: Chronic pain is a significant welfare concern in cats, and neuropathic pain, which arises from aberrant processing of sensory signals within the nervous system, is a subcategory of this type of pain. To comprehend this condition and how multimodal pharmacotherapy plays a central role in alleviating discomfort, it is crucial to delve into the anatomy of nociception and pain perception. In addition, there is an intricate interplay between emotional health and chronic pain in cats, and understanding and addressing the emotional factors that contribute to pain perception, and vice versa, is essential for comprehensive care.Clinical approach:Neuropathic pain is suspected if there is abnormal sensation in the area of the distribution of pain, together with a positive response to trial treatment with drugs effective for neuropathic pain. Ideally, this clinical suspicion would be supported by confirmation of a lesion at this neurolocalisation using diagnostic modalities such as MRI and neuroelectrophysiology. Alternatively, there may be a history of known trauma at that site. A variety of therapies, including analgesic, anti-inflammatory and adjuvant drugs, and neuromodulation (eg, TENS or acupuncture), can be employed to address different facets of pain pathways.Aim:This review article, aimed at primary care/ general practitioners, focuses on the identification and management of neuropathic pain in cats. Three case vignettes are included and a structured treatment algorithm is presented to guide veterinarians in tailoring interventions.Evidence base:The review draws on current literature, where available, along with the author\'s extensive experience and research.
摘要：
■慢性疼痛是猫的重大福利问题，和神经性疼痛，它源于神经系统内感觉信号的异常处理，是这类疼痛的一个子类别。要理解这种情况以及多模式药物治疗如何在缓解不适方面发挥核心作用，深入研究伤害性感受和疼痛感知的解剖学至关重要。此外,猫的情绪健康和慢性疼痛之间存在复杂的相互作用，理解和解决导致疼痛感知的情感因素，反之亦然,对于全面护理至关重要。临床方法：如果疼痛分布区域有异常感觉，则怀疑神经性疼痛，以及对神经性疼痛有效药物的试验治疗反应积极。理想情况下,这种临床怀疑可以通过使用MRI和神经电生理学等诊断方法在神经定位时确认病变来支持.或者，那个部位可能有已知的外伤史.各种各样的疗法，包括镇痛药,抗炎和辅助药物，和神经调节(例如，TENS或针灸），可以用来解决疼痛途径的不同方面。目的：这篇评论文章，针对初级保健/全科医生，专注于猫神经性疼痛的识别和管理。包括三个案例小插曲，并提出了一种结构化的治疗算法，以指导兽医量身定制干预措施。证据基础：这篇综述借鉴了当前的文献，如果可用，以及作者的丰富经验和研究。
