Abstract：
OBJECTIVE: Breast cancer, a prevalent global malignancy in women, necessitates a comprehensive treatment approach, with surgery playing a crucial role. Severe acute pain is common post-radical breast cancer surgery, emphasizing the significance of hemodynamic stability and postoperative pain control for optimal outcomes. This study evaluates the impact of ultrasound-guided erector spinae plane block (ESPB) on these parameters in ASA scores 1-2 patients undergoing modified radical breast cancer surgery with general anesthesia.
METHODS: Forty-eight patients were divided into two groups: a general anesthesia group, with erector spinae plane block (GA+ESPB), and a control group receiving only general anesthesia (GA). Hemodynamic parameters were continuously monitored, and postoperative pain was assessed using the visual analog scale (VAS) at various time points.
RESULTS: Ultrasound-guided ESPB effectively maintained hemodynamic stability and reduced postoperative pain in breast cancer surgery patients. Statistically significant differences were observed in heart rate, systolic and diastolic blood pressure, and mean arterial pressure between the GA and GA+ESPB groups at multiple time points (p < 0.05). VAS scores showed a significant interaction time*group (p < 0.001), with consistent differences between the groups at all time points (p ≤ 0.001).
CONCLUSIONS: Ultrasound-guided ESPB application proved effective in preserving hemodynamic stability and managing postoperative pain in modified radical breast cancer surgery. The technique demonstrates promise in minimizing complications related to hemodynamic variations and postoperative pain, contributing to a comprehensive approach to breast cancer surgical treatment.
METHODS: Forty-eight patients were divided into two groups: a general anesthesia group, with erector spinae plane block (GA+ESPB), and a control group receiving only general anesthesia (GA). Hemodynamic parameters were continuously monitored, and postoperative pain was assessed using the visual analog scale (VAS) at various time points.
RESULTS: Ultrasound-guided ESPB effectively maintained hemodynamic stability and reduced postoperative pain in breast cancer surgery patients. Statistically significant differences were observed in heart rate, systolic and diastolic blood pressure, and mean arterial pressure between the GA and GA+ESPB groups at multiple time points (p < 0.05). VAS scores showed a significant interaction time*group (p < 0.001), with consistent differences between the groups at all time points (p ≤ 0.001).
CONCLUSIONS: Ultrasound-guided ESPB application proved effective in preserving hemodynamic stability and managing postoperative pain in modified radical breast cancer surgery. The technique demonstrates promise in minimizing complications related to hemodynamic variations and postoperative pain, contributing to a comprehensive approach to breast cancer surgical treatment.
摘要：
目标：乳腺癌，女性普遍存在的全球恶性肿瘤，需要综合治疗的方法，手术起着至关重要的作用。严重急性疼痛是乳腺癌根治术后常见的，强调血流动力学稳定性和术后疼痛控制对最佳结果的重要性。这项研究评估了超声引导下的竖脊肌平面阻滞（ESPB）对ASA评分1-2的全麻改良根治术乳腺癌患者这些参数的影响。
方法:48例患者分为两组:全麻组,与竖脊肌平面块（GA+ESPB），对照组仅接受全身麻醉（GA）。连续监测血流动力学参数，术后疼痛采用视觉模拟量表(VAS)在不同时间点进行评估.
结果：超声引导下的ESPB能有效维持乳腺癌手术患者的血流动力学稳定，减轻术后疼痛。在心率方面观察到有统计学意义的差异，收缩压和舒张压,GA组和GA+ESPB组在多个时间点的平均动脉压（p<0.05）。VAS评分显示显著的相互作用时间*组(p<0.001)，在所有时间点，组间差异一致（p≤0.001）。
结论：超声引导下应用ESPB在乳腺癌改良根治术中可有效保持血流动力学稳定性和控制术后疼痛。该技术有望最大限度地减少与血流动力学变化和术后疼痛相关的并发症，有助于乳腺癌手术治疗的综合方法。
方法:48例患者分为两组:全麻组,与竖脊肌平面块（GA+ESPB），对照组仅接受全身麻醉（GA）。连续监测血流动力学参数，术后疼痛采用视觉模拟量表(VAS)在不同时间点进行评估.
结果：超声引导下的ESPB能有效维持乳腺癌手术患者的血流动力学稳定，减轻术后疼痛。在心率方面观察到有统计学意义的差异，收缩压和舒张压,GA组和GA+ESPB组在多个时间点的平均动脉压（p<0.05）。VAS评分显示显著的相互作用时间*组(p<0.001)，在所有时间点，组间差异一致（p≤0.001）。
结论：超声引导下应用ESPB在乳腺癌改良根治术中可有效保持血流动力学稳定性和控制术后疼痛。该技术有望最大限度地减少与血流动力学变化和术后疼痛相关的并发症，有助于乳腺癌手术治疗的综合方法。
