PDF(Pubmed)
Abstract：
UNASSIGNED: The pathology of and mechanisms underlying muscle degeneration remain unclear. We aimed to quantitatively evaluate the natural changes in fatty infiltration and muscle atrophy in patients with chronic rotator cuff tears using 3-dimensional 2-point Dixon magnetic resonance imaging.
UNASSIGNED: Thirty patients with nonoperatively observed rotator cuff tears without tear extension were evaluated using multiple magnetic resonance imaging examinations with a minimum interval of 2 years. The fatty infiltration ratio (%fat) and muscle volume of the rotator cuff muscles were compared between the 2 examinations in those with supraspinatus (SSP) tear <2 cm (<2 cm SSP group), SSP tear ≥2 cm (≥2 cm SSP group), and massive tear (massive group). The SSP) infraspinatus, and teres minor (ISP + TM), and subscapularis muscles were evaluated.
UNASSIGNED: The massive group showed a significantly greater %fat than the <2 and ≥2 cm SSP groups in the SSP (P = .002) and ISP + TM muscles (P < .001). The total muscle volume did not differ among the 3 groups for all rotator cuff muscle components. The %fat values did not change in any rotator cuff components during the follow-up period in all groups. The total muscle volume in the massive group significantly decreased in the SSP (P = .018) and ISP + TM muscles (P = .013).
UNASSIGNED: The present results indicate that fatty infiltration of the torn muscle occurs in the early phase after a rotator cuff tear, whereas muscle atrophy appears to progress gradually in chronic rotator cuff tears. Early intervention before muscle degeneration should be considered if the tear involves the infraspinatus tendon.
UNASSIGNED: Thirty patients with nonoperatively observed rotator cuff tears without tear extension were evaluated using multiple magnetic resonance imaging examinations with a minimum interval of 2 years. The fatty infiltration ratio (%fat) and muscle volume of the rotator cuff muscles were compared between the 2 examinations in those with supraspinatus (SSP) tear <2 cm (<2 cm SSP group), SSP tear ≥2 cm (≥2 cm SSP group), and massive tear (massive group). The SSP) infraspinatus, and teres minor (ISP + TM), and subscapularis muscles were evaluated.
UNASSIGNED: The massive group showed a significantly greater %fat than the <2 and ≥2 cm SSP groups in the SSP (P = .002) and ISP + TM muscles (P < .001). The total muscle volume did not differ among the 3 groups for all rotator cuff muscle components. The %fat values did not change in any rotator cuff components during the follow-up period in all groups. The total muscle volume in the massive group significantly decreased in the SSP (P = .018) and ISP + TM muscles (P = .013).
UNASSIGNED: The present results indicate that fatty infiltration of the torn muscle occurs in the early phase after a rotator cuff tear, whereas muscle atrophy appears to progress gradually in chronic rotator cuff tears. Early intervention before muscle degeneration should be considered if the tear involves the infraspinatus tendon.
摘要：
■肌肉变性的病理和机制尚不清楚。我们旨在使用3维2点Dixon磁共振成像定量评估慢性肩袖撕裂患者脂肪浸润和肌肉萎缩的自然变化。
■使用多次磁共振成像检查对30例非手术观察到肩袖撕裂而无撕裂延伸的患者进行了评估，最小间隔为2年。比较冈上肌（SSP）撕裂<2cm（<2cmSSP组）的2次检查中肩袖肌肉的脂肪浸润率（％脂肪）和肌肉体积，SSP撕裂≥2cm（SSP组≥2cm），和大量的眼泪（大量的群体）。SSP)下棘，和小调(ISP+TM)，评估肩胛骨下肌。
■在SSP（P=.002）和ISPTM肌肉（P<.001）中，大量组的脂肪百分比明显高于<2和≥2cmSSP组。对于所有肩袖肌肉成分，3组之间的总肌肉体积没有差异。在所有组的随访期间，任何肩袖组件的脂肪百分比值都没有变化。在SSP(P=.018)和ISP+TM肌肉(P=.013)中,大量组的总肌肉体积显著降低。
■目前的结果表明，撕裂肌肉的脂肪浸润发生在肩袖撕裂后的早期阶段，而肌肉萎缩在慢性肩袖撕裂中似乎逐渐进展。如果撕裂涉及冈下肌腱，则应考虑在肌肉变性之前进行早期干预。
■使用多次磁共振成像检查对30例非手术观察到肩袖撕裂而无撕裂延伸的患者进行了评估，最小间隔为2年。比较冈上肌（SSP）撕裂<2cm（<2cmSSP组）的2次检查中肩袖肌肉的脂肪浸润率（％脂肪）和肌肉体积，SSP撕裂≥2cm（SSP组≥2cm），和大量的眼泪（大量的群体）。SSP)下棘，和小调(ISP+TM)，评估肩胛骨下肌。
■在SSP（P=.002）和ISPTM肌肉（P<.001）中，大量组的脂肪百分比明显高于<2和≥2cmSSP组。对于所有肩袖肌肉成分，3组之间的总肌肉体积没有差异。在所有组的随访期间，任何肩袖组件的脂肪百分比值都没有变化。在SSP(P=.018)和ISP+TM肌肉(P=.013)中,大量组的总肌肉体积显著降低。
■目前的结果表明，撕裂肌肉的脂肪浸润发生在肩袖撕裂后的早期阶段，而肌肉萎缩在慢性肩袖撕裂中似乎逐渐进展。如果撕裂涉及冈下肌腱，则应考虑在肌肉变性之前进行早期干预。
