Lower Limb Deep Venous Thrombosis After Posterior Spinal Fusion as an Initial Manifestation of Factor V Leiden Mutation in a Pediatric Patient: A Case Report.

后路脊柱融合术后下肢深静脉血栓形成作为儿科患者因子 V Leiden 突变的初始表现 ： 病例报告。

• 发表时间: 2024 Apr
• 来源期刊: Cureus
• DOI: 10.7759/cureus.57543
• PMID: 38707128
• 文章类型: Case Reports
• 作者列表: Cortes-Nieves CJ,Ramirez N,Nieves A,Ramírez N

关键词: deep venous thrombosis (dvt); heterozygous factor v leiden; heterozygous factor v leiden mutation; posterior spinal fusion; scoliosis surgery

Abstract

Deep venous thrombosis (DVT) is a serious condition in which a blood clot forms in a deep vein, usually of the lower extremity. In pediatric orthopedic surgery, the incidence of thrombotic events is rare. This is a case presentation of a 12-year-old female patient without previous events or a family history of thrombotic events who underwent a posterior spinal fusion due to severe adolescent idiopathic scoliosis. The patient developed a DVT due to an underlying Factor V Leiden mutation. The purpose of this case report is to create awareness, facilitate the diagnosis and management, and aid in future interventions and clinical outcomes.

摘要

深静脉血栓（DVT）是一种严重的疾病，在深静脉中形成血凝块，通常是下肢。在小儿骨科手术中，血栓事件的发生率很少.这是一个12岁女性患者的病例报告，该患者以前没有事件或有血栓性事件家族史，由于严重的青少年特发性脊柱侧凸而接受了后路脊柱融合术。患者由于潜在的因子VLeiden突变而发展为DVT。这个案例报告的目的是建立意识，便于诊断和管理，并有助于未来的干预措施和临床结果。