PDF(Pubmed)
Abstract：
BACKGROUND: Human papillomavirus (HPV) infection is a prevalent sexually transmitted infection globally, with significant associations with various cancers. Despite the availability of HPV vaccines, vaccination uptake remains suboptimal in many regions, including Saudi Arabia.
METHODS: This cross-sectional survey-based study aimed to assess perceptions, attitudes, and barriers related to HPV vaccination among residents in different regions of Saudi Arabia. Participants were recruited using a stratified sampling method, and data were collected through a structured questionnaire administered electronically.
RESULTS: A total of 600 participants were included in the study, with diverse demographic profiles observed. The largest age group was 26-35 years old, comprising 42.7% (n = 256) of the sample. The distribution of gender was approximately equal, with 54.7% (n = 328) male participants. Notable perception and knowledge about HPV were observed, with 49.7% (n = 298) reporting being very familiar. Furthermore, 85.8% (n = 515) believed that HPV could cause serious health problems, and 63.7% (n = 382) perceived the vaccine to be very effective. Positive attitudes toward HPV vaccination were prevalent, with a significant proportion expressing a willingness to recommend the vaccine to themselves (70.0%, n = 420) and their children (65.0%, n = 390). Healthcare provider recommendation emerged as a key influencing factor, with 73.8% (n = 443) citing it as influential. Despite favorable attitudes, barriers to HPV vaccination were reported, including vaccine cost (22.5%, n = 135) and lack of awareness (13.7%, n = 82). However, a substantial proportion of unvaccinated participants cited not applicable reasons (57.2%, n = 343), indicating prior vaccination. Factors associated with HPV vaccination uptake included higher education levels, with those holding a master\'s degree or above exhibiting higher odds of vaccination uptake (OR (odds ratio): 1.80, 95% CI (confidence interval): 1.35-2.40, p < 0.001). Age (26-35 vs. 18-25) also showed a borderline significant association (OR: 1.25, 95% CI: 0.98-1.60, p = 0.074).
CONCLUSIONS: The study highlights the importance of understanding perceptions and barriers to HPV vaccination to inform public health policies and programs in Saudi Arabia. Addressing identified barriers, such as educational campaigns and improving access to vaccination services, is essential for enhancing HPV vaccination coverage and reducing the burden of HPV-related diseases in the region.
METHODS: This cross-sectional survey-based study aimed to assess perceptions, attitudes, and barriers related to HPV vaccination among residents in different regions of Saudi Arabia. Participants were recruited using a stratified sampling method, and data were collected through a structured questionnaire administered electronically.
RESULTS: A total of 600 participants were included in the study, with diverse demographic profiles observed. The largest age group was 26-35 years old, comprising 42.7% (n = 256) of the sample. The distribution of gender was approximately equal, with 54.7% (n = 328) male participants. Notable perception and knowledge about HPV were observed, with 49.7% (n = 298) reporting being very familiar. Furthermore, 85.8% (n = 515) believed that HPV could cause serious health problems, and 63.7% (n = 382) perceived the vaccine to be very effective. Positive attitudes toward HPV vaccination were prevalent, with a significant proportion expressing a willingness to recommend the vaccine to themselves (70.0%, n = 420) and their children (65.0%, n = 390). Healthcare provider recommendation emerged as a key influencing factor, with 73.8% (n = 443) citing it as influential. Despite favorable attitudes, barriers to HPV vaccination were reported, including vaccine cost (22.5%, n = 135) and lack of awareness (13.7%, n = 82). However, a substantial proportion of unvaccinated participants cited not applicable reasons (57.2%, n = 343), indicating prior vaccination. Factors associated with HPV vaccination uptake included higher education levels, with those holding a master\'s degree or above exhibiting higher odds of vaccination uptake (OR (odds ratio): 1.80, 95% CI (confidence interval): 1.35-2.40, p < 0.001). Age (26-35 vs. 18-25) also showed a borderline significant association (OR: 1.25, 95% CI: 0.98-1.60, p = 0.074).
CONCLUSIONS: The study highlights the importance of understanding perceptions and barriers to HPV vaccination to inform public health policies and programs in Saudi Arabia. Addressing identified barriers, such as educational campaigns and improving access to vaccination services, is essential for enhancing HPV vaccination coverage and reducing the burden of HPV-related diseases in the region.
摘要：
背景：人乳头瘤病毒（HPV）感染是全球流行的性传播感染，与各种癌症有显著关联。尽管有HPV疫苗，在许多地区，疫苗接种摄入量仍然欠佳，包括沙特阿拉伯。
方法：这项基于横断面调查的研究旨在评估感知，态度，以及沙特阿拉伯不同地区居民与HPV疫苗接种相关的障碍。参与者是使用分层抽样方法招募的，数据是通过电子管理的结构化问卷收集的。
结果：共有600名参与者被纳入研究，观察到不同的人口统计学特征。最大的年龄组是26-35岁，包含42.7%(n=256)的样品。性别分布大致相等，54.7%（n=328）男性参与者。观察到对HPV的显著感知和知识，49.7%(n=298)的报告非常熟悉。此外，85.8％（n=515）认为HPV可能导致严重的健康问题，63.7%(n=382)的人认为疫苗非常有效。对HPV疫苗接种的积极态度很普遍，相当比例的人表示愿意向自己推荐疫苗(70.0%，n=420)和他们的孩子(65.0%，n=390）。医疗保健提供者的推荐成为一个关键的影响因素，73.8%(n=443)的人认为它有影响力。尽管态度有利，据报道，HPV疫苗接种的障碍，包括疫苗成本(22.5%，n=135)和缺乏意识(13.7%，n=82）。然而,相当比例的未接种疫苗的参与者列举了不适用的原因(57.2%，n=343)，表明之前的疫苗接种。与HPV疫苗接种相关的因素包括较高的教育水平，那些持有硕士或以上学位的人表现出更高的接种几率(OR(比值比):1.80,95%CI(置信区间):1.35-2.40,p<0.001)。年龄（26-35vs.18-25）也显示出临界显着的关联（OR：1.25，95％CI：0.98-1.60，p=0.074）。
结论：该研究强调了了解HPV疫苗接种的认知和障碍的重要性，以告知沙特阿拉伯的公共卫生政策和计划。解决已确定的障碍，例如教育运动和改善获得疫苗接种服务的机会，对于提高HPV疫苗接种覆盖率和减少该地区HPV相关疾病的负担至关重要。
方法：这项基于横断面调查的研究旨在评估感知，态度，以及沙特阿拉伯不同地区居民与HPV疫苗接种相关的障碍。参与者是使用分层抽样方法招募的，数据是通过电子管理的结构化问卷收集的。
结果：共有600名参与者被纳入研究，观察到不同的人口统计学特征。最大的年龄组是26-35岁，包含42.7%(n=256)的样品。性别分布大致相等，54.7%（n=328）男性参与者。观察到对HPV的显著感知和知识，49.7%(n=298)的报告非常熟悉。此外，85.8％（n=515）认为HPV可能导致严重的健康问题，63.7%(n=382)的人认为疫苗非常有效。对HPV疫苗接种的积极态度很普遍，相当比例的人表示愿意向自己推荐疫苗(70.0%，n=420)和他们的孩子(65.0%，n=390）。医疗保健提供者的推荐成为一个关键的影响因素，73.8%(n=443)的人认为它有影响力。尽管态度有利，据报道，HPV疫苗接种的障碍，包括疫苗成本(22.5%，n=135)和缺乏意识(13.7%，n=82）。然而,相当比例的未接种疫苗的参与者列举了不适用的原因(57.2%，n=343)，表明之前的疫苗接种。与HPV疫苗接种相关的因素包括较高的教育水平，那些持有硕士或以上学位的人表现出更高的接种几率(OR(比值比):1.80,95%CI(置信区间):1.35-2.40,p<0.001)。年龄（26-35vs.18-25）也显示出临界显着的关联（OR：1.25，95％CI：0.98-1.60，p=0.074）。
结论：该研究强调了了解HPV疫苗接种的认知和障碍的重要性，以告知沙特阿拉伯的公共卫生政策和计划。解决已确定的障碍，例如教育运动和改善获得疫苗接种服务的机会，对于提高HPV疫苗接种覆盖率和减少该地区HPV相关疾病的负担至关重要。
