PDF(Pubmed)
Abstract：
Constipation is common in the diseases of the digestive system in clinics. With the change in diet structure and the increase in life pressure, the prevalence rate increases year by year. In traditional Chinese medicine (TCM), the location of the disease of constipation is in the large intestine, which is related to the dysfunction of lung, spleen, liver, kidney and other viscera. Its pathogenesis is conductive dysfunction of large intestine. Based on the theory, Shouhui Tongbian Capsule (SHTB) is composed of eight traditional Chinese medicines, including Polygoni multiflori Radix (Heshouwu in Chinese), Aloe (Luhui in Chinese), Cassiae Semen (Juemingzi in Chinese), Ginseng Radix et Rhizoma (Renshen in Chinese), Lycii Fructus (Gouqizi in Chinese), Asini Corii Colla (Ejiao in Chinese), Aurantii Fructus Immaturus (Zhishi in Chinese), and Atractylodis Macrocephalae Rhizoma (Baizhu in Chinese), which could help to release excessive turbid, and nourishing yin and supplementing qi in the treatment. This study has been carried out to review the latest advances of SHTB in the treatment of constipation. The results showed that significant effect of SHTB was found in the treatment of constipation, such as functional constipation, and constipation associated with tumor chemotherapy, colitis, type 2 diabetes and chronic cardiac failure. Besides, obvious adverse reactions were not observed. SHTB could effectively treat five types of constipation, provide direction for the future exploration of SHTB in the treatment of other types of constipation.
摘要：
便秘常见于临床消化系统疾病。随着饮食结构的改变和生活压力的增加,患病率逐年上升。在中医（TCM），便秘的部位在大肠,这与肺功能障碍有关，脾,脾肝脏,肾脏和其他内脏。其发病机制为大肠传导功能障碍。基于理论,寿辉通便胶囊（SHTB）由八种中药组成，包括何首乌（中文为何首乌），芦荟，决明子,人参(中国人参),枸杞(中文名:谷奇子),AsiniCoriiColla（中国的阿胶），栀子(中国的芝士),白术（白术），这可能有助于释放过多的浑浊，并在治疗中滋阴益气。本文对SHTB治疗便秘的最新进展进行综述。结果表明,SHTB治疗便秘效果显著,比如功能性便秘，与肿瘤化疗相关的便秘，结肠炎,2型糖尿病和慢性心力衰竭。此外,未观察到明显的不良反应。SHTB可以有效治疗五种类型的便秘，为今后探索SHTB治疗其他类型便秘提供方向。
