PDF(Pubmed)
Abstract：
UNASSIGNED: Non-traumatic ectopia lentis is a rare ocular disorder usually associated with syndromes like Marfans\'s syndrome, Weil-Marchesani and Homocystinuria. Ectopia lentis can lead to profound visual loss from refractive errors, glaucoma as well as retinal detachment if left unattended.
UNASSIGNED: The aim of this study was to describe the clinical profile of patients with non-traumatic ectopia lentis in a paediatric ophthalmology clinic in Ibadan, Nigeria.
UNASSIGNED: The clinical records of children ≤16 years diagnosed with non- traumatic ectopia lentis at the Paediatric Ophthalmology Clinic, University College Hospital Ibadan, from May 1, 2015 to Dec 31, 2019 were retrospectively reviewed. Information on demography, family history, visual acuity (VA), mean refractive error (spherical equivalent), and management was retrieved.
UNASSIGNED: Clinical records of 25 patients were reviewed. The mean age was 8.9 (±3.41) years with a range of 2-15 years. Sixteen (64%) patients were males. All the patients had bilateral involvement. A positive family history of ectopia lentis was elicited in 6 (24%) patients. Thirteen (52%) patients had a Marfanoid habitus and superior displacement of the lens was observed in 26 (52%) eyes. The presenting visual acuity was <6/60 in 22 (44%) eyes. The spherical equivalent of the refractive errors ranged from -20.00DS to +13.25DS. Twenty (40%) eyes underwent surgery within the period of the study and the best corrected postoperative visual acuity improved by 2 or more lines in 12 (60%) of operated eyes.
UNASSIGNED: Severe visual morbidity was common in this cohort of patients with ectopia lentis in our practice. Treatment provided some improvement in vision which highlights the need to encourage early presentation for care. Detailed family history is important as a few of the patients were diagnosed following acceptance of our invitation to siblings for ophthalmic evaluation.
UNASSIGNED: The aim of this study was to describe the clinical profile of patients with non-traumatic ectopia lentis in a paediatric ophthalmology clinic in Ibadan, Nigeria.
UNASSIGNED: The clinical records of children ≤16 years diagnosed with non- traumatic ectopia lentis at the Paediatric Ophthalmology Clinic, University College Hospital Ibadan, from May 1, 2015 to Dec 31, 2019 were retrospectively reviewed. Information on demography, family history, visual acuity (VA), mean refractive error (spherical equivalent), and management was retrieved.
UNASSIGNED: Clinical records of 25 patients were reviewed. The mean age was 8.9 (±3.41) years with a range of 2-15 years. Sixteen (64%) patients were males. All the patients had bilateral involvement. A positive family history of ectopia lentis was elicited in 6 (24%) patients. Thirteen (52%) patients had a Marfanoid habitus and superior displacement of the lens was observed in 26 (52%) eyes. The presenting visual acuity was <6/60 in 22 (44%) eyes. The spherical equivalent of the refractive errors ranged from -20.00DS to +13.25DS. Twenty (40%) eyes underwent surgery within the period of the study and the best corrected postoperative visual acuity improved by 2 or more lines in 12 (60%) of operated eyes.
UNASSIGNED: Severe visual morbidity was common in this cohort of patients with ectopia lentis in our practice. Treatment provided some improvement in vision which highlights the need to encourage early presentation for care. Detailed family history is important as a few of the patients were diagnosed following acceptance of our invitation to siblings for ophthalmic evaluation.
摘要：
■非创伤性外翻是一种罕见的眼部疾病，通常与马范氏综合症等综合症有关，Weil-Marchesani和高半胱氨酸尿症。屈光不正会导致严重的视力丧失，如果无人看管，青光眼以及视网膜脱离。
■这项研究的目的是描述在伊巴丹的儿科眼科诊所中患有非创伤性外翻的患者的临床特征，尼日利亚。
■在儿科眼科诊所诊断为非创伤性外翻的≤16岁儿童的临床记录，大学学院医院伊巴丹，从2015年5月1日至2019年12月31日进行回顾性审查.关于人口统计的信息，家族史,视敏度（VA），平均屈光不正（等效球面），并恢复了管理。
■回顾了25例患者的临床记录。平均年龄为8.9（±3.41）岁，范围为2-15岁。16名（64％）患者为男性。所有患者均有双侧受累。6例（24％）患者出现外翻家族史。13例（52％）患者患有Marfanoid习性，并且在26例（52％）眼中观察到晶状体移位。22只(44%)眼的视力<6/60。屈光不正的球面当量范围为-20.00DS至+13.25DS。在研究期间，有20只（40％）眼接受了手术，并且在12只（60％）的手术眼中，最佳的矫正术后视力提高了2行或更多行。
■在我们的实践中，严重的视力发病率在这个队列中很常见。治疗改善了视力，这突出了鼓励早期护理的必要性。详细的家族史很重要，因为接受我们邀请兄弟姐妹进行眼科评估后，才诊断出一些患者。
■这项研究的目的是描述在伊巴丹的儿科眼科诊所中患有非创伤性外翻的患者的临床特征，尼日利亚。
■在儿科眼科诊所诊断为非创伤性外翻的≤16岁儿童的临床记录，大学学院医院伊巴丹，从2015年5月1日至2019年12月31日进行回顾性审查.关于人口统计的信息，家族史,视敏度（VA），平均屈光不正（等效球面），并恢复了管理。
■回顾了25例患者的临床记录。平均年龄为8.9（±3.41）岁，范围为2-15岁。16名（64％）患者为男性。所有患者均有双侧受累。6例（24％）患者出现外翻家族史。13例（52％）患者患有Marfanoid习性，并且在26例（52％）眼中观察到晶状体移位。22只(44%)眼的视力<6/60。屈光不正的球面当量范围为-20.00DS至+13.25DS。在研究期间，有20只（40％）眼接受了手术，并且在12只（60％）的手术眼中，最佳的矫正术后视力提高了2行或更多行。
■在我们的实践中，严重的视力发病率在这个队列中很常见。治疗改善了视力，这突出了鼓励早期护理的必要性。详细的家族史很重要，因为接受我们邀请兄弟姐妹进行眼科评估后，才诊断出一些患者。
