PDF(Pubmed)
Abstract：
A patient presented with overlapping clinical and laboratory features of 2 rare autoinflammatory diseases, NLRP1-associated autoinflammation with arthritis and dyskeratosis and familial multiple self-healing palmoplantar carcinoma. Her severe inflammatory attack was treated with the IL-1 receptor-α inhibitor anakinra along with the Janus kinase inhibitor ruxolitinib. Three years into the treatment, the patient\'s inflammatory symptoms are completely in remission.
摘要：
患者表现为2种罕见的自身炎症性疾病的临床和实验室特征重叠，NLRP1相关的自身炎症与关节炎和角化不良和家族性多发性自愈掌plant癌。她的严重炎症发作用IL-1受体-α抑制剂anakinra和Janus激酶抑制剂ruxolitinib治疗。治疗三年后，患者的炎症症状完全缓解。
