Abstract：
Spontaneous preterm birth (sPTB) is a complex and clinically heterogeneous condition that remains incompletely understood, leading to insufficient interventions to effectively prevent it from occurring. Cell-free ribonucleic acid signatures in the maternal circulation have the potential to identify biologically relevant subtypes of sPTB. These could one day be used to predict and prevent sPTB in asymptomatic individuals, and to aid in prognosis and management for individuals presenting with threatened preterm labor and preterm prelabor rupture of membranes.
摘要：
自发性早产（sPTB）是一种复杂且临床上异质的疾病，尚不完全了解。导致干预措施不足，无法有效预防这种情况的发生。母体循环中的无细胞核糖核酸特征具有鉴定sPTB的生物学相关亚型的潜力。这些有一天可以用来预测和预防无症状个体的sPTB，并帮助预测和管理的个体有先兆早产和早产胎膜破裂。
