Abstract：
OBJECTIVE: The aim of this systematic review was to assess the role of hyperbaric oxygen therapy (HBOT) in patients with dysphagia after radiation therapy for head and neck cancer.
METHODS: A systematic search was conducted in the electronic databases Ovid MEDLINE, Ovid Embase, and Cochrane Central Register of Controlled Trials for relevant studies until March 14, 2023. No restriction on language or publication date. The criteria for inclusion: patients with HNC who had received both radiation therapy and HBOT as 1) a preventive treatment against swallowing difficulties, 2) to preserve swallowing function, or 3) to promote swallowing difficulties.
RESULTS: We identified 1396 records. After removal of 31 duplicates, 1365 records were accessible for title and abstract screening. This yielded 53 studies for full text assessment. Six studies met the eligibility criteria and were included for qualitative analysis.
CONCLUSIONS: Evidence of HBOT benefits in patients with dysphagia after radiation therapy for head and neck cancer is inconsistent. Well-designed studies using validated outcome measures and long-term follow-up are warranted.
METHODS: A systematic search was conducted in the electronic databases Ovid MEDLINE, Ovid Embase, and Cochrane Central Register of Controlled Trials for relevant studies until March 14, 2023. No restriction on language or publication date. The criteria for inclusion: patients with HNC who had received both radiation therapy and HBOT as 1) a preventive treatment against swallowing difficulties, 2) to preserve swallowing function, or 3) to promote swallowing difficulties.
RESULTS: We identified 1396 records. After removal of 31 duplicates, 1365 records were accessible for title and abstract screening. This yielded 53 studies for full text assessment. Six studies met the eligibility criteria and were included for qualitative analysis.
CONCLUSIONS: Evidence of HBOT benefits in patients with dysphagia after radiation therapy for head and neck cancer is inconsistent. Well-designed studies using validated outcome measures and long-term follow-up are warranted.
摘要：
目的：本系统综述旨在评估高压氧治疗（HBOT）在头颈部肿瘤放疗后吞咽困难患者中的作用。
方法：在电子数据库OvidMEDLINE中进行了系统搜索，OvidEmbase,和Cochrane中央对照试验登记册进行相关研究，直到2023年3月14日。语言或出版日期没有限制。纳入标准：接受放射治疗和HBOT的HNC患者1）对吞咽困难的预防性治疗，2）保持吞咽功能，或3)促进吞咽困难。
结果：我们确定了1396条记录。删除31个副本后，1365条记录可用于标题和摘要筛选。这产生了53个研究全文评估。六项研究符合资格标准，并被纳入定性分析。
结论：头颈部肿瘤放疗后吞咽困难患者HBOT获益的证据不一致。使用经过验证的结果测量和长期随访的精心设计的研究是必要的。
方法：在电子数据库OvidMEDLINE中进行了系统搜索，OvidEmbase,和Cochrane中央对照试验登记册进行相关研究，直到2023年3月14日。语言或出版日期没有限制。纳入标准：接受放射治疗和HBOT的HNC患者1）对吞咽困难的预防性治疗，2）保持吞咽功能，或3)促进吞咽困难。
结果：我们确定了1396条记录。删除31个副本后，1365条记录可用于标题和摘要筛选。这产生了53个研究全文评估。六项研究符合资格标准，并被纳入定性分析。
结论：头颈部肿瘤放疗后吞咽困难患者HBOT获益的证据不一致。使用经过验证的结果测量和长期随访的精心设计的研究是必要的。
