关键词: Biomedical Cellulose Chitosan Polysaccharides Starch Wound care

Mesh : Wound Healing / drug effects Polysaccharides / chemistry therapeutic use Humans Biocompatible Materials / chemistry therapeutic use Animals Hydrogels / chemistry therapeutic use Bandages Nanocomposites / chemistry therapeutic use Chitosan / chemistry

来  源:   DOI:10.1016/j.ijbiomac.2024.132048

Abstract:
Polysaccharides are favourable and promising biopolymers for wound care applications due to their abundant natural availability, low cost and excellent biocompatibility. They possess different functional groups, such as carboxylic, hydroxyl and amino, and can easily be modified to obtain the desirable properties and various forms. This review systematically analyses the recent progress in polysaccharides derived materials for wound care applications, emphasizing the most commonly used cellulose, chitosan, alginate, starch, dextran and hyaluronic acid derived materials. The distinctive attributes of each polysaccharide derived wound care material are discussed in detail, along with their different forms, i.e., films, membranes, sponges, nanoemulsions, nanofibers, scaffolds, nanocomposites and hydrogels. The processing methods to develop polysaccharides derived wound care materials are also summarized. In the end, challenges related to polysaccharides derived materials in wound care management are listed, and suggestions are given to expand their utilization in the future to compete with conventional wound healing materials.
摘要:
由于其丰富的天然可用性,多糖是伤口护理应用的有利和有前途的生物聚合物。低成本和优异的生物相容性。它们拥有不同的官能团,如羧基,羟基和氨基,并且可以容易地修改以获得期望的性质和各种形式。这篇综述系统地分析了多糖衍生材料在伤口护理中的应用的最新进展,强调最常用的纤维素,壳聚糖,海藻酸盐,淀粉,葡聚糖和透明质酸衍生材料。详细讨论了每种多糖衍生的伤口护理材料的独特属性,以及它们不同的形式,即,电影,膜,海绵,纳米乳液,纳米纤维,脚手架,纳米复合材料和水凝胶。还总结了开发多糖衍生的伤口护理材料的加工方法。最后,列出了与创伤护理管理中的多糖衍生材料相关的挑战,并提出了未来扩大其利用率以与常规伤口愈合材料竞争的建议。
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