关键词: ACS-NSQIP Hepatectomy Metastasis Prediction Risk calculator

Mesh : Adult Aged Female Humans Male Middle Aged Asia, Southeastern Colorectal Neoplasms / pathology surgery Hepatectomy Length of Stay Liver Neoplasms / surgery secondary Postoperative Complications / epidemiology Retrospective Studies Risk Assessment Southeast Asian People

来  源:   DOI:10.1007/s00423-024-03331-x

Abstract:
OBJECTIVE: This study evaluated the accuracy of the American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) calculator in predicting outcomes after hepatectomy for colorectal cancer (CRC) liver metastasis in a Southeast Asian population.
METHODS: Predicted and actual outcomes were compared for 166 patients undergoing hepatectomy for CRC liver metastasis identified between 2017 and 2022, using receiver operating characteristic curves with area under the curve (AUC) and Brier score.
RESULTS: The ACS-NSQIP calculator accurately predicted most postoperative complications (AUC > 0.70), except for surgical site infection (AUC = 0.678, Brier score = 0.045). It also exhibited satisfactory performance for readmission (AUC = 0.818, Brier score = 0.011), reoperation (AUC = 0.945, Brier score = 0.002), and length of stay (LOS, AUC = 0.909). The predicted LOS was close to the actual LOS (5.9 vs. 5.0 days, P = 0.985).
CONCLUSIONS: The ACS-NSQIP calculator demonstrated generally accurate predictions for 30-day postoperative outcomes after hepatectomy for CRC liver metastasis in our patient population.
摘要:
目的:本研究评估了美国外科医生学会国家外科质量改进计划(ACS-NSQIP)计算器在预测东南亚人群结直肠癌(CRC)肝转移肝切除术后预后的准确性。
方法:使用具有曲线下面积(AUC)和Brier评分的受试者工作特征曲线,比较了2017年至2022年期间因CRC肝转移而接受肝切除术的166例患者的预测和实际结果。
结果:ACS-NSQIP计算器准确预测了大多数术后并发症(AUC>0.70),手术部位感染除外(AUC=0.678,Brier评分=0.045)。它还表现出令人满意的再入院表现(AUC=0.818,Brier评分=0.011),再次手术(AUC=0.945,Brier评分=0.002),和停留时间(LOS,AUC=0.909)。预测的LOS接近实际的LOS(5.9vs.5.0天,P=0.985)。
结论:ACS-NSQIP计算器显示了我们的患者群体对CRC肝转移肝切除术后30天预后的总体准确预测。
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