关键词: Bilirubin disorders Neonatal and paediatric intensive care Neonatal health Pediatrics

Mesh : Humans Infant, Newborn Exchange Transfusion, Whole Blood Infant, Small for Gestational Age Respiration, Artificial Transfusion-Related Acute Lung Injury / etiology diagnosis

来  源:   DOI:10.1136/bcr-2024-259748   PDF(Pubmed)

Abstract:
We report a successful case where a newborn with transfusion-related acute lung injury following an exchange transfusion was effectively treated using conservative methods, eliminating the need for surfactant therapy. Very few instances of this complication have been documented globally. A low birth weight, small for gestational age, term neonate, diagnosed with hyperbilirubinaemia due to Rh incompatibility, experienced sudden respiratory distress in the form of severe retractions, tachypnoea and cyanosis 3 hours after the procedure. Neonate required mechanical ventilation on the grounds of mixed acidosis and diffuse alveolar infiltrates on the chest radiograph. The medical team suspected and treated the baby for transfusion-related acute lung injury through conservative measures. Transfusion-related acute lung injury, an acute life-threatening complication of blood component transfusion, can exhibit symptoms in neonates that are frequently misinterpreted as sepsis. The baby was discharged in good health after successful management after 19 days.
摘要:
我们报告了一个成功的病例,其中使用保守方法有效治疗了交换输血后输血相关急性肺损伤的新生儿。消除表面活性剂治疗的需要。很少有这种并发症的情况在全球范围内得到记录。低出生体重,小于胎龄,学期新生儿,由于Rh不相容而被诊断为高胆红素血症,经历了严重缩回形式的突然呼吸窘迫,手术后3小时呼吸急促和紫癜。新生儿因混合酸中毒和胸片上弥漫性肺泡浸润而需要机械通气。医疗小组怀疑并通过保守措施治疗婴儿与输血相关的急性肺损伤。输血相关急性肺损伤,一种危及生命的急性输血并发症,在新生儿中可以表现出经常被误解为败血症的症状。19天后成功管理后,婴儿身体健康。
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