Neonatal sepsis with meningitis, ventriculitis and brain abscess caused by Edwardsiella tarda.

新生儿败血症伴脑膜炎,迟钝爱德华菌引起的脑室炎和脑脓肿。

• 发表时间: 2024 May 3
• 来源期刊: BMJ Case Rep
• DOI: 10.1136/bcr-2022-254028
• PMID: 38702069
• 文章类型: Case Reports
• 作者列表: Geibel EM,Pearce MR,Zabrocki L,Thompson C

关键词: Meningitis; Neonatal and paediatric intensive care

Mesh: Humans; Infant, Newborn; Anti-Bacterial Agents / therapeutic use; Brain Abscess / microbiology; Cerebral Ventriculitis / microbiology diagnosis drug therapy; Edwardsiella tarda / isolation & purification; Enterobacteriaceae Infections / diagnosis complications drug therapy; Meningitis / microbiology diagnosis; Meningitis, Bacterial / microbiology diagnosis drug therapy complications; Neonatal Sepsis / microbiology diagnosis

Abstract

A case of neonatal sepsis caused by Edwardsiella tarda, an uncommon pathogen typically associated with aquatic lifeforms, is described. The infant presented in septic shock with seizures and respiratory failure and was found to have meningitis, ventriculitis and a brain abscess requiring drainage. Only a small number of case reports of neonatal E. tarda infection, several with sepsis with poor auditory or neurodevelopmental outcomes or meningitis, have been described in the literature. This case report suggests that E. tarda, while uncommon, can be a cause of serious central nervous system disease in the neonatal population and that an aggressive approach to pursuing and treating complications may lead to improved neurodevelopmental outcomes.

摘要

塔达爱德华氏菌致新生儿败血症一例,一种罕见的病原体，通常与水生生物有关，被描述。该名婴儿出现败血性休克，伴有癫痫发作和呼吸衰竭，并被发现患有脑膜炎，脑室炎和需要引流的脑脓肿。只有少数病例报告新生儿塔达大肠杆菌感染，一些患有败血症，听觉或神经发育不良或脑膜炎，已在文献中描述。这个病例报告表明E.tarda,虽然不常见，可能是新生儿人群严重中枢神经系统疾病的原因，积极的追求和治疗并发症的方法可能会改善神经发育结果。