关键词: Administered activity Decay chain Decay data Dose calibrator Gamma counter Half-life Precision medicine Primary standard Progeny ingrowth Ra-223 Targeted alpha therapy Th-227

来  源:   DOI:10.1016/j.apradiso.2024.111326

Abstract:
Thorium-227 was separated from its progeny and standardized for activity by the triple-to-double coincidence ratio (TDCR) method of liquid scintillation counting. Confirmatory liquid scintillation-based measurements were made using efficiency tracing with 3H and live-timed anticoincidence counting (LTAC). The separation time and the efficiency of the separation were confirmed by gamma-ray spectrometry. Calibrations for reentrant pressurized ionization chambers, including commercial radionuclide calibrators, and a well-type NaI(Tl) detector are discussed.
摘要:
将Thium-227从其后代中分离出来,并通过液体闪烁计数的三双重合比(TDCR)方法对活性进行标准化。使用3H效率追踪和实时定时反符合计数(LTAC)进行基于液体闪烁的验证性测量。分离时间和分离效率通过伽马射线光谱法证实。折返加压电离室的校准,包括商业放射性核素校准器,讨论了井型NaI(Tl)探测器。
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