PDF(Pubmed)
Abstract：
Interstitial lung diseases (ILDs) refer to a heterogeneous and complex group of conditions characterized by inflammation, fibrosis, or both, in the interstitium of the lungs. This results in impaired gas exchange, leading to a worsening of respiratory symptoms and a decline in lung function. While the etiology of some ILDs is unclear, most cases can be traced back to factors such as genetic predispositions, environmental exposures (including allergens, toxins, and air pollution), underlying autoimmune diseases, or the use of certain medications. There has been an increase in research and evidence aimed at identifying etiology, understanding epidemiology, improving clinical diagnosis, and developing both pharmacological and non-pharmacological treatments. This review provides a comprehensive overview of the current state of knowledge in the field of interstitial lung diseases.
摘要：
间质性肺病（ILD）是指一组以炎症为特征的异质性和复杂的疾病，纤维化，或者两者兼而有之,在肺间质.这导致气体交换受损，导致呼吸道症状恶化和肺功能下降。虽然一些ILD的病因尚不清楚，大多数病例可以追溯到遗传易感性等因素，环境暴露(包括过敏原，毒素,和空气污染)，潜在的自身免疫性疾病，或使用某些药物。旨在确定病因的研究和证据有所增加，了解流行病学，改善临床诊断，并开发药物和非药物治疗。这篇综述全面概述了间质性肺病领域的知识现状。
