Abstract：
The global increasing spread of multidrug-resistant organisms (MRDOs) is threatening the control of various infections in vulnerable populations and patient groups. One of the most affected groups is burn patients, who are prone to hyperinfection as they suffer from a hypermetabolic state and weakened immune barriers. Those patients also share the infection risk of patients hospitalized for a long time, including ventilator-associated pneumonia and urinary tract infections. While some preventative and therapeutic management styles are still controversial, there are some consensuses that we discuss here. In this review, we aim to present the current knowledge on multidrug-resistance with a special focus on burn patients, discuss various causative organisms and their treatment options, and highlight the importance of antibiotic stewardship and teamwork in responding to an outbreak of MDROs.
摘要：
耐多药生物（MRDO）在全球范围内的传播正在威胁着对脆弱人群和患者群体中各种感染的控制。受影响最大的群体之一是烧伤患者，他们容易过度感染，因为他们患有高代谢状态和减弱的免疫屏障。这些患者也分担了长期住院患者的感染风险，包括呼吸机相关性肺炎和尿路感染。虽然一些预防和治疗管理方式仍然存在争议，我们在这里讨论一些共识。在这次审查中,我们的目标是介绍当前关于多药耐药性的知识，特别关注烧伤患者，讨论各种致病生物及其治疗方案，并强调抗生素管理和团队合作在应对MDROs爆发中的重要性。
