PDF(Pubmed)
Abstract：
UNASSIGNED: Tuberculosis (TB) has been one of the most devastating diseases to humanity in recent decades; although pulmonary infection is the most common, infection of any other organ is familiar as well. Colon cancer is another disease affecting the gastrointestinal (GI) system and mostly targets people over 50. Only a few studies mentioned the co-existence of cancer and TB occurring at the same place and time. Hence, the authors report a rare case of concurrent ascending colon adenocarcinoma and colonic TB.
UNASSIGNED: A 49 -year-old man presented to our clinic with constipation and abdominal pain. Two colonoscopies were performed, and two biopsies were taken; the first one showed granulomatous inflammation consistent with TB, and the second one showed low-grade adenocarcinoma. Computed tomography showed annular thickening of the ascending colon with infiltrates around the lesions. A right hemicolectomy was performed, and the final pathology confirmed adenocarcinoma grade II and extensive TB granulomas involving the colon into the serosa and the lymph nodes. Anti-TB medications were administered after surgery.
UNASSIGNED: Due to appropriate diagnostic methods, TB and cancer were detected at an early stage. In our treatment protocol, no adjuvant chemotherapy was applied after surgery due to the possibility of drug interaction with anti-TB medications.
UNASSIGNED: The two diseases may co-exist; thus, diagnosing them may not be the easiest, not to mention the lack of a clear treatment protocol in case of their accompany.
UNASSIGNED: A 49 -year-old man presented to our clinic with constipation and abdominal pain. Two colonoscopies were performed, and two biopsies were taken; the first one showed granulomatous inflammation consistent with TB, and the second one showed low-grade adenocarcinoma. Computed tomography showed annular thickening of the ascending colon with infiltrates around the lesions. A right hemicolectomy was performed, and the final pathology confirmed adenocarcinoma grade II and extensive TB granulomas involving the colon into the serosa and the lymph nodes. Anti-TB medications were administered after surgery.
UNASSIGNED: Due to appropriate diagnostic methods, TB and cancer were detected at an early stage. In our treatment protocol, no adjuvant chemotherapy was applied after surgery due to the possibility of drug interaction with anti-TB medications.
UNASSIGNED: The two diseases may co-exist; thus, diagnosing them may not be the easiest, not to mention the lack of a clear treatment protocol in case of their accompany.
摘要：
■结核病（TB）是近几十年来对人类最具破坏性的疾病之一；尽管肺部感染是最常见的疾病，任何其他器官的感染也是熟悉的。结肠癌是另一种影响胃肠道（GI）系统的疾病，主要针对50岁以上的人群。只有少数研究提到癌症和结核病在同一地点和时间共存。因此，作者报告了一例罕见的同时发生升结肠腺癌和结肠TB的病例.
■一位49岁的男子因便秘和腹痛出现在我们的诊所。进行了两次结肠镜检查，进行了两次活检；第一次显示肉芽肿性炎症与TB一致，第二个显示为低度腺癌。计算机断层扫描显示升结肠环形增厚，病变周围有浸润。进行了右半结肠切除术,最终病理证实为II级腺癌和广泛的TB肉芽肿，累及结肠浆膜和淋巴结。手术后给予抗结核药物。
■由于适当的诊断方法，结核病和癌症在早期被发现。在我们的治疗方案中,由于药物可能与抗结核药物相互作用,手术后未应用辅助化疗.
■这两种疾病可能共存；因此，诊断他们可能不是最容易的,更不用说在他们陪伴的情况下缺乏明确的治疗方案。
■一位49岁的男子因便秘和腹痛出现在我们的诊所。进行了两次结肠镜检查，进行了两次活检；第一次显示肉芽肿性炎症与TB一致，第二个显示为低度腺癌。计算机断层扫描显示升结肠环形增厚，病变周围有浸润。进行了右半结肠切除术,最终病理证实为II级腺癌和广泛的TB肉芽肿，累及结肠浆膜和淋巴结。手术后给予抗结核药物。
■由于适当的诊断方法，结核病和癌症在早期被发现。在我们的治疗方案中,由于药物可能与抗结核药物相互作用,手术后未应用辅助化疗.
■这两种疾病可能共存；因此，诊断他们可能不是最容易的,更不用说在他们陪伴的情况下缺乏明确的治疗方案。
