PDF(Pubmed)
Abstract：
UNASSIGNED: Cardiovascular disease (CVD) is a major cause of death and disability among patients with type 2 diabetes, especially in low-income and middle-income countries. Type 2 diabetes mellitus (T2DM) patients have a 2-4-fold increased risk of CVD. There is limited data about cardiovascular disease risks and its determinants among T2DM patients in Ethiopia. This study aimed to identify possible predictors of cardiovascular diseases among adults with T2DM in southern Ethiopia.
UNASSIGNED: A hospital-based unmatched case-control study was conducted at southern Ethiopia Arbaminch Hospital on 196 randomly selected patients with type 2 diabetes on follow-up (98 cases and 98 controls). The authors collected data using a structured interviewer-administered questionnaire, laboratory checklist, and additional document review of T2DM patients. A multivariable binary logistic regression was fitted to identify cardiovascular disease determinants, and the findings were presented using an adjusted odds ratio (AOR) with a 95% CI.
UNASSIGNED: The mean reported age (±SD) of the cases and the controls was 56.3.3 (±8.9) and 52.3 (±9.3) years, respectively. The two identified independent determinants of cardiovascular disease with AOR [95% CI] were hypertension [AOR=4.953, 95% CI (2.47, 9.93) and persistent urine albuminuria [AOR=12.9, 95% CI (3.98, 41.7)].
UNASSIGNED: This study showed that having high blood pressure and persistent urine albuminuria are independent predictors of cardiovascular disease in T2DM patients. The current study setting needs an intervention for mitigating these cardiovascular disease determinants.
UNASSIGNED: A hospital-based unmatched case-control study was conducted at southern Ethiopia Arbaminch Hospital on 196 randomly selected patients with type 2 diabetes on follow-up (98 cases and 98 controls). The authors collected data using a structured interviewer-administered questionnaire, laboratory checklist, and additional document review of T2DM patients. A multivariable binary logistic regression was fitted to identify cardiovascular disease determinants, and the findings were presented using an adjusted odds ratio (AOR) with a 95% CI.
UNASSIGNED: The mean reported age (±SD) of the cases and the controls was 56.3.3 (±8.9) and 52.3 (±9.3) years, respectively. The two identified independent determinants of cardiovascular disease with AOR [95% CI] were hypertension [AOR=4.953, 95% CI (2.47, 9.93) and persistent urine albuminuria [AOR=12.9, 95% CI (3.98, 41.7)].
UNASSIGNED: This study showed that having high blood pressure and persistent urine albuminuria are independent predictors of cardiovascular disease in T2DM patients. The current study setting needs an intervention for mitigating these cardiovascular disease determinants.
摘要：
心血管疾病（CVD）是2型糖尿病患者死亡和残疾的主要原因，特别是在低收入和中等收入国家。2型糖尿病（T2DM）患者的CVD风险增加2-4倍。关于埃塞俄比亚T2DM患者心血管疾病风险及其决定因素的数据有限。本研究旨在确定埃塞俄比亚南部成人T2DM患者心血管疾病的可能预测因子。
在埃塞俄比亚南部Arbaminch医院进行了一项基于医院的无匹配病例对照研究，对196名随机选择的2型糖尿病患者进行了随访（98例和98例对照）。作者使用结构化的面试官管理的问卷收集数据，实验室检查表,和T2DM患者的额外文件审查。多变量二元逻辑回归拟合以确定心血管疾病的决定因素，研究结果采用校正比值比(AOR),CI为95%.
■病例和对照组的平均报告年龄（±SD）分别为56.3.3（±8.9）和52.3（±9.3）岁，分别。确定的AOR[95%CI]心血管疾病的两个独立决定因素是高血压[AOR=4.953,95%CI(2.47,9.93)和持续性尿白蛋白[AOR=12.9,95%CI(3.98,41.7)]。
■这项研究表明，高血压和持续的尿白蛋白是T2DM患者心血管疾病的独立预测因子。当前的研究环境需要一种干预措施来减轻这些心血管疾病的决定因素。
在埃塞俄比亚南部Arbaminch医院进行了一项基于医院的无匹配病例对照研究，对196名随机选择的2型糖尿病患者进行了随访（98例和98例对照）。作者使用结构化的面试官管理的问卷收集数据，实验室检查表,和T2DM患者的额外文件审查。多变量二元逻辑回归拟合以确定心血管疾病的决定因素，研究结果采用校正比值比(AOR),CI为95%.
■病例和对照组的平均报告年龄（±SD）分别为56.3.3（±8.9）和52.3（±9.3）岁，分别。确定的AOR[95%CI]心血管疾病的两个独立决定因素是高血压[AOR=4.953,95%CI(2.47,9.93)和持续性尿白蛋白[AOR=12.9,95%CI(3.98,41.7)]。
■这项研究表明，高血压和持续的尿白蛋白是T2DM患者心血管疾病的独立预测因子。当前的研究环境需要一种干预措施来减轻这些心血管疾病的决定因素。
