METHODS: Data were reviewed for 1250 consecutive patients undergoing TRUS-Bx at the Charlie Norwood VA Medical Center from January 2017 to January 2023. Needle washing was adopted in February 2021. Complications occurring within 30 days after TRUS-Bx were recorded.
RESULTS: There were 912 patients in group 1 (without needle washing) and 338 in group 2 (with needle washing). Groups had equivalent demographic features, and men of African descent comprised 70% of patients. Standard 12 core biopsies were done in 83% and 82% in groups 1 and 2, respectively (p = 0.788). Total complication rates were 4% and 2% in groups 1 and 2, respectively (p = 0.077). There were 13 sepsis events in group 1 (1.4%) and none in group 2 (p = 0.027). Clavien-Dindo Grade I-III complications occurred in 25 (2.7%) and 7 (2.1%) patients in groups 1 and 2, respectively (p = 0.505). Standard antibiotic prophylaxis (PO fluoroquinolone and IM gentamicin) was given in 80% and 86% of patients in groups 1 and 2, respectively (p = 0.030). Subset analysis limited to patients who received standard prophylaxis showed a significant difference in sepsis rates (1.5% vs 0%; p = 0.036).
CONCLUSIONS: Adoption of isopropyl alcohol needle washing was associated with a significant decrease in PBS events.
方法:对2017年1月至2023年1月在查理诺伍德VA医学中心接受TRUS-Bx的1250名连续患者的数据进行了回顾。2021年2月采用洗针。记录TRUS-Bx后30天内发生的并发症。
结果:第1组(未洗针)912例,第2组(洗针)338例。群体具有同等的人口统计特征,非洲裔男性占患者的70%。在第1组和第2组中分别有83%和82%的标准12个核心活检(p=0.788)。第1组和第2组的总并发症发生率分别为4%和2%(p=0.077)。第1组有13例脓毒症事件(1.4%),第2组无脓毒症事件(p=0.027)。Clavien-DindoI-III级并发症分别发生在第1组和第2组中的25例(2.7%)和7例(2.1%)患者中(p=0.505)。在第1组和第2组中,分别有80%和86%的患者接受了标准抗生素预防(PO氟喹诺酮和IM庆大霉素)(p=0.030)。仅限于接受标准预防的患者的子集分析显示,败血症发生率存在显着差异(1.5%vs0%;p=0.036)。
结论:采用异丙醇针头清洗与PBS事件的显著减少相关。