Abstract：
UNASSIGNED: To review the presentation and visual prognostic factors of patients with endogenous endophthalmitis before and after the introduction of microincision vitrectomy surgery (MIVS), at a tertiary referral hospital in Taiwan, over a 21-year period.
UNASSIGNED: We retrospectively analyzed medical records of patients diagnosed with endogenous endophthalmitis before and after the introduction of MIVS between January 2002 and December 2022.
UNASSIGNED: Data were collected from 147 patients. Diabetes mellitus was the most common comorbidity (59.9%). Liver abscess (32.7%) was the leading source of infection, followed by urinary tract infection (15.0%), and infective endocarditis (5.4%). Klebsiella pneumoniae (50.4%) was the most common pathogen, followed by Staphylococcus aureus (13.5%), and Candida albicans (8.3%). Poor initial visual acuity worse than counting fingers (CF) (p < 0.001) and diabetes mellitus (p = 0.008) were significantly associated with poor visual outcomes. In the treatment of 98 patients with poor initial visual acuity worse than CF, the proportion of vitrectomy surgeries performed increased from 13/56 (23.2%) to 24/42 (57.1%) (p = 0.001) after the introduction of MIVS. Final visual acuity of CF or better increased from 7/56 (12.5%) to 12/42 (28.6%) after the introduction of MIVS (p = 0.046). Vitrectomy was a better prognostic factor for final visual outcome in patients with poor initial visual acuity of worse than CF (p = 0.011) than other factors.
UNASSIGNED: In endogenous endophthalmitis patients presenting with poor initial visual acuity, vitrectomy was a better visual prognostic factor. MIVS has allowed more patients to undergo vitrectomy and improved visual outcomes.
UNASSIGNED: We retrospectively analyzed medical records of patients diagnosed with endogenous endophthalmitis before and after the introduction of MIVS between January 2002 and December 2022.
UNASSIGNED: Data were collected from 147 patients. Diabetes mellitus was the most common comorbidity (59.9%). Liver abscess (32.7%) was the leading source of infection, followed by urinary tract infection (15.0%), and infective endocarditis (5.4%). Klebsiella pneumoniae (50.4%) was the most common pathogen, followed by Staphylococcus aureus (13.5%), and Candida albicans (8.3%). Poor initial visual acuity worse than counting fingers (CF) (p < 0.001) and diabetes mellitus (p = 0.008) were significantly associated with poor visual outcomes. In the treatment of 98 patients with poor initial visual acuity worse than CF, the proportion of vitrectomy surgeries performed increased from 13/56 (23.2%) to 24/42 (57.1%) (p = 0.001) after the introduction of MIVS. Final visual acuity of CF or better increased from 7/56 (12.5%) to 12/42 (28.6%) after the introduction of MIVS (p = 0.046). Vitrectomy was a better prognostic factor for final visual outcome in patients with poor initial visual acuity of worse than CF (p = 0.011) than other factors.
UNASSIGNED: In endogenous endophthalmitis patients presenting with poor initial visual acuity, vitrectomy was a better visual prognostic factor. MIVS has allowed more patients to undergo vitrectomy and improved visual outcomes.
摘要：
■回顾内源性眼内炎患者在采用微切口玻璃体切割手术（MVS）前后的表现和视觉预后因素，在台湾的三级转诊医院，在21年的时间里。
■我们回顾性分析了在2002年1月至2022年12月期间引入MVS前后诊断为内源性眼内炎的患者的医疗记录。
■数据来自147名患者。糖尿病是最常见的合并症（59.9％）。肝脓肿（32.7%）是主要的感染源，其次是尿路感染（15.0%），感染性心内膜炎（5.4%）。肺炎克雷伯菌(50.4%)是最常见的病原菌,其次是金黄色葡萄球菌(13.5%)，和白色念珠菌(8.3%)。初始视力差于数指（CF）（p<0.001）和糖尿病（p=0.008）与不良的视力结果显着相关。在治疗98例差的患者中，初始视力比CF差，引入MVS后,进行玻璃体切割手术的比例从13/56(23.2%)增加到24/42(57.1%)(p=0.001).引入MIVS后，CF或更好的最终视力从7/56（12.5％）增加到12/42（28.6％）（p=0.046）。对于初始视力比CF差（p=0.011）的患者，玻璃体切除术是最终视力预后更好的预后因素。
■在初始视力较差的内源性眼内炎患者中，玻璃体切除术是较好的视觉预后因素.MIVS允许更多的患者接受玻璃体切除术并改善视力。
■我们回顾性分析了在2002年1月至2022年12月期间引入MVS前后诊断为内源性眼内炎的患者的医疗记录。
■数据来自147名患者。糖尿病是最常见的合并症（59.9％）。肝脓肿（32.7%）是主要的感染源，其次是尿路感染（15.0%），感染性心内膜炎（5.4%）。肺炎克雷伯菌(50.4%)是最常见的病原菌,其次是金黄色葡萄球菌(13.5%)，和白色念珠菌(8.3%)。初始视力差于数指（CF）（p<0.001）和糖尿病（p=0.008）与不良的视力结果显着相关。在治疗98例差的患者中，初始视力比CF差，引入MVS后,进行玻璃体切割手术的比例从13/56(23.2%)增加到24/42(57.1%)(p=0.001).引入MIVS后，CF或更好的最终视力从7/56（12.5％）增加到12/42（28.6％）（p=0.046）。对于初始视力比CF差（p=0.011）的患者，玻璃体切除术是最终视力预后更好的预后因素。
■在初始视力较差的内源性眼内炎患者中，玻璃体切除术是较好的视觉预后因素.MIVS允许更多的患者接受玻璃体切除术并改善视力。
