关键词: Impacted tooth lesions Ki-67 proliferative potential metaplasia unerupted tooth

来  源:   DOI:10.4103/njms.njms_214_22   PDF(Pubmed)

Abstract:
Tooth impaction is a frequent phenomenon, and the prevalence and distribution of this entity in different regions of the jaws may vary considerably. The third molars, maxillary canines, maxillary and mandibular premolars, and maxillary central incisors are the most commonly affected teeth. Impacted teeth in children and adolescents are rarely associated with pathological changes, but the prevalence of problems has been found to increase in later decades. Impacted teeth are commonly asymptomatic and not associated with any pathologic lesions for years. Proliferative potential of various odontogenic lesions were calculated using Ki-67 labeling index calculation, with the highest index of Unicystic Ameloblastoma followed by Adenomatoid odontogenic tumor, Unicystic Ameloblastoma, followed by the dental follicle. Ki-67 is a marker of cell proliferation, used as an important diagnostic marker in the pathologic differentiation of various lesions. It is always better to orthodontically treat or extract asymptomatic impacted teeth to avoid or to restrict the proliferative capacity of the dental follicle. Treatment decisions about the third molar have important clinical and cost implications.
摘要:
牙齿嵌塞是一种常见的现象,并且该实体在颌骨不同区域的患病率和分布可能差异很大。第三磨牙,上颌犬,上颌和下颌前磨牙,上颌中切牙是最常见的牙齿。儿童和青少年患牙很少与病理变化相关,但是发现问题的普遍性在随后的几十年中有所增加。受累牙齿通常无症状,多年来与任何病理病变无关。使用Ki-67标记指数计算计算各种牙源性病变的增殖潜力,单囊性成釉细胞瘤指数最高,其次是腺瘤样牙源性肿瘤,单囊性成釉细胞瘤,其次是牙囊。Ki-67是细胞增殖的标志物,用作各种病变病理分化的重要诊断标记物。总是更好地进行正畸治疗或提取无症状的患牙,以避免或限制牙囊的增殖能力。关于第三磨牙的治疗决定具有重要的临床和成本影响。
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