PDF(Pubmed)
Abstract：
BACKGROUND: Chronic myelomonocytic leukemia (CMML) complicated with Sweet syndrome (SS) is a rare hematological neoplasm. However, cases of concomitant development of perianal necrotizing SS (NSS) have not been reported.
METHODS: We report a case of a 49-year-old male patient who underwent sequential procedures for hemorrhoids and perianal abscess. He developed postoperative incision infection and was referred to the department where the authors work. Initially, perianal necrotizing fasciitis secondary to incision infection after perianal abscess surgery was suspected. Despite receiving antibiotic therapy and undergoing surgical debridement, deeper necrotic areas formed in the patient\'s perianal wounds, accompanied by persistent high fever. Blood and fungal cultures yielded negative results. The final diagnosis was corrected to be CMML with suspected concomitant perianal NSS.
CONCLUSIONS: CMML with perianal NSS is a rare condition, often misdiagnosed as perianal abscess or perianal necrotizing fasciitis. Conventional antibiotic therapy and surgical debridement are ineffective in managing this condition.
METHODS: We report a case of a 49-year-old male patient who underwent sequential procedures for hemorrhoids and perianal abscess. He developed postoperative incision infection and was referred to the department where the authors work. Initially, perianal necrotizing fasciitis secondary to incision infection after perianal abscess surgery was suspected. Despite receiving antibiotic therapy and undergoing surgical debridement, deeper necrotic areas formed in the patient\'s perianal wounds, accompanied by persistent high fever. Blood and fungal cultures yielded negative results. The final diagnosis was corrected to be CMML with suspected concomitant perianal NSS.
CONCLUSIONS: CMML with perianal NSS is a rare condition, often misdiagnosed as perianal abscess or perianal necrotizing fasciitis. Conventional antibiotic therapy and surgical debridement are ineffective in managing this condition.
摘要：
背景：慢性粒单核细胞白血病（CMML）合并Sweet综合征（SS）是一种罕见的血液肿瘤。然而,同时发生肛周坏死性SS（NSS）的病例尚未报道。
方法：我们报告了一例49岁男性患者，该患者接受了痔疮和肛周脓肿的序贯手术。他发生了术后切口感染，并被转诊到作者工作的部门。最初，怀疑肛周脓肿手术后切口感染继发的肛周坏死性筋膜炎。尽管接受了抗生素治疗并接受了手术清创术，在病人的肛周伤口形成的较深的坏死区域，伴有持续高烧。血液和真菌培养产生阴性结果。最终诊断被纠正为CMML，怀疑伴有肛周NSS。
结论：CMML合并肛周NSS是一种罕见的疾病，常误诊为肛周脓肿或肛周坏死性筋膜炎。传统的抗生素治疗和手术清创术对控制这种情况无效。
方法：我们报告了一例49岁男性患者，该患者接受了痔疮和肛周脓肿的序贯手术。他发生了术后切口感染，并被转诊到作者工作的部门。最初，怀疑肛周脓肿手术后切口感染继发的肛周坏死性筋膜炎。尽管接受了抗生素治疗并接受了手术清创术，在病人的肛周伤口形成的较深的坏死区域，伴有持续高烧。血液和真菌培养产生阴性结果。最终诊断被纠正为CMML，怀疑伴有肛周NSS。
结论：CMML合并肛周NSS是一种罕见的疾病，常误诊为肛周脓肿或肛周坏死性筋膜炎。传统的抗生素治疗和手术清创术对控制这种情况无效。
