Mesh : Humans Antibiotic Prophylaxis Bone Neoplasms / therapy surgery Chondrosarcoma / therapy Medical Oncology Orthopedics Prosthesis-Related Infections / therapy etiology Reoperation

来  源:   DOI:10.1302/0301-620X.106B5.BJJ-2023-1381

Abstract:
Chondrosarcoma is the second most common surgically treated primary bone sarcoma. Despite a large number of scientific papers in the literature, there is still significant controversy about diagnostics, treatment of the primary tumour, subtypes, and complications. Therefore, consensus on its day-to-day treatment decisions is needed. In January 2024, the Birmingham Orthopaedic Oncology Meeting (BOOM) attempted to gain global consensus from 300 delegates from over 50 countries. The meeting focused on these critical areas and aimed to generate consensus statements based on evidence amalgamation and expert opinion from diverse geographical regions. In parallel, periprosthetic joint infection (PJI) in oncological reconstructions poses unique challenges due to factors such as adjuvant treatments, large exposures, and the complexity of surgery. The meeting debated two-stage revisions, antibiotic prophylaxis, managing acute PJI in patients undergoing chemotherapy, and defining the best strategies for wound management and allograft reconstruction. The objectives of the meeting extended beyond resolving immediate controversies. It sought to foster global collaboration among specialists attending the meeting, and to encourage future research projects to address unsolved dilemmas. By highlighting areas of disagreement and promoting collaborative research endeavours, this initiative aims to enhance treatment standards and potentially improve outcomes for patients globally. This paper sets out some of the controversies and questions that were debated in the meeting.
摘要:
软骨肉瘤是第二常见的经手术治疗的原发性骨肉瘤。尽管文献中有大量的科学论文,关于诊断仍然存在重大争议,原发性肿瘤的治疗,亚型,和并发症。因此,需要就其日常治疗决定达成共识。2024年1月,伯明翰骨科肿瘤学会议(BOOM)试图获得来自50多个国家的300名代表的全球共识。会议侧重于这些关键领域,旨在根据不同地理区域的证据合并和专家意见,达成共识声明。并行,由于辅助治疗等因素,肿瘤重建中的假体周围感染(PJI)提出了独特的挑战,大曝光,以及手术的复杂性.会议就两阶段修订进行了辩论,抗生素预防,在接受化疗的患者中管理急性PJI,并确定伤口处理和同种异体移植重建的最佳策略。会议的目标不仅限于解决眼前的争议。它寻求促进出席会议的专家之间的全球合作,并鼓励未来的研究项目解决未解决的困境。通过突出分歧领域和促进合作研究努力,该计划旨在提高治疗标准,并有可能改善全球患者的结局.本文列出了会议中辩论的一些争议和问题。
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