Abstract：
UNASSIGNED: In oculoplastic surgery the eyelid tissue is frequently stretched in order to repair defects after tumor surgery. However, there is a paucity of research regarding how stretching affects eyelids. The purpose of this study was to gain insight into how traction force affects eyelid stretch as well as tissue perfusion, using a laser-based in vivo monitoring technique.
UNASSIGNED: Lower-lid pentagonal resections were performed in eight patients and a total of nine eyelids. The medial section of the eyelid was then stretched using a dynamometer up to a force of 2.3 Newtons (N), and eyelid stretching and blood perfusion were continuously measured using laser speckle contrast imaging.
UNASSIGNED: Tissue perfusion decreased exponentially when eyelid tissue was stretched, with an initial sharp decline followed by a more gradual reduction. Perfusion approached zero at a force of approximately 2.0 N. The length of the eyelid increased with increasing force up to 1.5 N, after which there was only a very slight increase in length.
UNASSIGNED: Eyelid tissue seems to respond to traction in a non-linear fashion, where the initial force results in the greatest eyelid stretching and reduction in blood perfusion. The results provide information on the effects of a large force for direct closure of large eyelid defects. Considering how quickly perfusion approaches zero, the high success rate of eyelid reconstruction surgery is likely a testament to the extensive vascularization of the periocular region.
UNASSIGNED: Lower-lid pentagonal resections were performed in eight patients and a total of nine eyelids. The medial section of the eyelid was then stretched using a dynamometer up to a force of 2.3 Newtons (N), and eyelid stretching and blood perfusion were continuously measured using laser speckle contrast imaging.
UNASSIGNED: Tissue perfusion decreased exponentially when eyelid tissue was stretched, with an initial sharp decline followed by a more gradual reduction. Perfusion approached zero at a force of approximately 2.0 N. The length of the eyelid increased with increasing force up to 1.5 N, after which there was only a very slight increase in length.
UNASSIGNED: Eyelid tissue seems to respond to traction in a non-linear fashion, where the initial force results in the greatest eyelid stretching and reduction in blood perfusion. The results provide information on the effects of a large force for direct closure of large eyelid defects. Considering how quickly perfusion approaches zero, the high success rate of eyelid reconstruction surgery is likely a testament to the extensive vascularization of the periocular region.
摘要：
在眼整形手术中，经常拉伸眼睑组织以修复肿瘤手术后的缺损。然而,关于伸展如何影响眼睑的研究很少。这项研究的目的是深入了解牵引力如何影响眼睑伸展以及组织灌注，使用基于激光的体内监测技术。
■对8例患者和总共9个眼睑进行了下睑五边形切除术。然后使用测力计将眼睑的内侧部分拉伸至2.3牛顿（N）的力，使用激光散斑对比成像连续测量眼睑伸展和血液灌注。
■当眼睑组织伸展时，组织灌注呈指数下降，最初的急剧下降，然后是更渐进的下降。灌注在大约2.0N的力下接近零。眼睑的长度随着力的增加而增加，直到1.5N，之后，长度只有很小的增加。
■眼睑组织似乎以非线性方式对牵引力做出反应，其中初始力导致最大的眼睑伸展和血液灌注减少。结果提供了有关直接闭合大眼睑缺损的较大力的影响的信息。考虑到灌注有多快接近零，眼睑重建手术的高成功率可能证明了眼周区域广泛的血管化。
■对8例患者和总共9个眼睑进行了下睑五边形切除术。然后使用测力计将眼睑的内侧部分拉伸至2.3牛顿（N）的力，使用激光散斑对比成像连续测量眼睑伸展和血液灌注。
■当眼睑组织伸展时，组织灌注呈指数下降，最初的急剧下降，然后是更渐进的下降。灌注在大约2.0N的力下接近零。眼睑的长度随着力的增加而增加，直到1.5N，之后，长度只有很小的增加。
■眼睑组织似乎以非线性方式对牵引力做出反应，其中初始力导致最大的眼睑伸展和血液灌注减少。结果提供了有关直接闭合大眼睑缺损的较大力的影响的信息。考虑到灌注有多快接近零，眼睑重建手术的高成功率可能证明了眼周区域广泛的血管化。
