PDF(Pubmed)
Abstract：
Nonocclusive mesenteric ischemia (NOMI) causes mesenteric ischemia and intestinal necrosis despite the absence of organic obstruction, such as thrombi and emboli in mesenteric blood vessels, and it has an extremely poor prognosis. We report a case of NOMI developed during bioradiotherapy (BRT) with cetuximab for cervical lymph node metastasis of tongue cancer. The patient was a 73-year-old man who underwent right radical neck dissection for neck lymph node metastasis after tongue cancer surgery. Postoperatively, the patient received BRT with cetuximab. On the 34th day after BRT, the patient had abdominal distension and a decreased level of consciousness. Contrast-enhanced computed tomography revealed mesenteric ischemia without thrombi and extensive intestinal emphysema. The patient was diagnosed with NOMI. Furthermore, he had septic shock and was treated with vasopressors and antibacterial agents; however, the condition of the patient did not improve, and he died on the same day.
摘要：
非闭塞性肠系膜缺血（NOMI）引起肠系膜缺血和肠坏死，尽管没有器质性梗阻，如肠系膜血管中的血栓和栓子，预后极差.我们报告了在使用西妥昔单抗进行生物放射疗法（BRT）治疗舌癌颈淋巴结转移期间发生的NOMI病例。该患者是一名73岁的男性，他在舌癌手术后因颈部淋巴结转移而接受了右根治性颈部清扫术。术后,患者接受BRT联合西妥昔单抗治疗.在BRT之后的第34天，患者出现腹胀和意识水平下降。对比增强计算机断层扫描显示肠系膜缺血，无血栓和广泛的肠气肿。患者被诊断为NOMI。此外，他患有感染性休克，并接受了血管加压药和抗菌剂治疗；然而，病人的情况没有改善，他在同一天死了.
