PDF(Pubmed)
Abstract：
Juvenile onset recurrent respiratory papillomatosis is a lifelong benign squamous lesion associated with HPV infection, particularly HPV6 and HPV11 genotypes. These lesions are rare, but can lead to laryngeal obturations, which can cause disabling dyspnea, or transform into squamous cell carcinoma. The aim here is to provide an epidemiological, biological and clinical overview of this pathology, particularly in children, in order to understand the issues at stake in terms of research and the development of medical and therapeutic management tools.
摘要：
幼年发作的复发性呼吸道乳头状瘤是与HPV感染相关的终生良性鳞状病变，特别是HPV6和HPV11基因型。这些病变很罕见,但是会导致喉阻塞，会导致呼吸困难，或者转变成鳞状细胞癌.这里的目的是提供一种流行病学，这种病理学的生物学和临床概述，特别是在儿童中，为了了解在研究和开发医疗和治疗管理工具方面的问题。
